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Titolo: Genetic alterations in human prostate cancer: A review of current literature
Autore: Ozen, M; Pathak, S;
- Indirizzi:
- Univ Texas, MD Anderson Canc Ctr, Cellular Genet Lab, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 Cellular Genet Lab, Houston, TX 77030 USA Univ Texas, MD Anderson Canc Ctr, Dept Lab Med, Houston, TX 77030 USA UnivTexas Houston TX USA 77030 Ctr, Dept Lab Med, Houston, TX 77030 USA
- Titolo Testata:
- ANTICANCER RESEARCH
fascicolo: 3B,
volume: 20,
anno: 2000,
pagine: 1905 - 1912
- SICI:
- 0250-7005(200005/06)20:3B<1905:GAIHPC>2.0.ZU;2-M
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- TUMOR-SUPPRESSOR GENE; IN-SITU HYBRIDIZATION; GROWTH-FACTOR-BETA; FAMILIAL ADENOMATOUS POLYPOSIS; P53 PROTEIN ACCUMULATION; TELOMERE LENGTH; SOMATIC MUTATIONS; CARCINOMA-CELLS; DNA-PLOIDY; CHROMOSOMAL INSTABILITY;
- Keywords:
- prostate cancer genetics; telomere; tumor suppressor genes; proto-oncogenes; malignant transformation;
- Tipo documento:
- Review
- Natura:
- Periodico
- Settore Disciplinare:
- Life Sciences
- Citazioni:
- 152
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Pathak, S Univ Texas, MD Anderson Canc Ctr, Cellular Genet Lab, 1515 Holcombe Blvd,Box 181, Houston, TX 77030 USA Univ Texas 1515 Holcombe Blvd,Box 181 Houston TX USA 77030 0 USA
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- Citazione:
- M. Ozen e S. Pathak, "Genetic alterations in human prostate cancer: A review of current literature", ANTICANC R, 20(3B), 2000, pp. 1905-1912
Abstract
We review the literature dealing with genetic alterations in human prostate cancer. We also discuss genetic predisposition and the roles of various proto-oncogenes and tumor-suppressor genes in prostate cancer initiation, progression, and metastasis. The role of telomere dynamics in prostate cancermetastasis and the induction of apoptosis is also briefly discussed.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 14:20:13