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Titolo:
Cyst wall enhancement in pilocytic astrocytoma: Neoplastic or reactive phenomena
Autore:
Beni-Adani, L; Gomori, M; Spektor, S; Constantini, S;
Indirizzi:
Tel Aviv Med Ctr, Dana Childrens Hosp, Dept Pediat Neurosurg, IL-64239 TelAviv, Israel Tel Aviv Med Ctr Tel Aviv Israel IL-64239 surg, IL-64239 TelAviv, Israel Hadassah Univ Hosp, Dept Neuroradiol, IL-91120 Jerusalem, Israel Hadassah Univ Hosp Jerusalem Israel IL-91120 IL-91120 Jerusalem, Israel
Titolo Testata:
PEDIATRIC NEUROSURGERY
fascicolo: 5, volume: 32, anno: 2000,
pagine: 234 - 239
SICI:
1016-2291(200005)32:5<234:CWEIPA>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
BENIGN CEREBELLAR ASTROCYTOMAS; TERM FOLLOW-UP; CEREBRAL HEMISPHERES; CHILDREN; CHILDHOOD;
Keywords:
cystic pilocytic astrocytoma; JPA; MRI; prognosis; surgery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Beni-Adani, L Tel Aviv Med Ctr, Dana Childrens Hosp, Dept Pediat Neurosurg, 6 Weizman St, IL-64239 Tel Aviv, Israel Tel Aviv Med Ctr 6 Weizman St TelAviv Israel IL-64239 rael
Citazione:
L. Beni-Adani et al., "Cyst wall enhancement in pilocytic astrocytoma: Neoplastic or reactive phenomena", PED NEUROS, 32(5), 2000, pp. 234-239

Abstract

Cystic pilocytic astrocytomas (CPA) consist of a mural nodule and an accompanying cyst, which may prominently enhance on MRI after contrast administration. This raises the question whether an enhanced wall represents a tumorand thus should be resected together with the solid nodule, as radical tumor surgery is associated with better prognosis. Until now, no systematic histopathological examinations of cyst walls have been reported in correlation with MRI, intraoperative appearance and postoperative clinical and MRI follow-up. We present 3 patients with CPAs and brightly enhanced cyst walls on MRI. Because of the benign, transparent appearance of the cyst wall intraoperatively, it was biopsied but not resected, and only radical removal of the nodule and its immediate surroundings was performed. Separate specimenstaken from the cyst wall showed no tumor. MRI performed annually, up to 48-56 months after surgery showed no recurrence of the cyst or the tumor. In such cases of CPA, we suggest that enhancement of cyst walls may represent reactive rather than tumoral tissue, and may be left intact without riskingworse prognosis. Mechanisms leading to cyst wall enhancement and the optimal surgical treatment are discussed. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/01/20 alle ore 19:48:49