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Titolo:
DERIVATIZATION REACTIONS FOR NEUROTRANSMITTERS AND THEIR AUTOMATION
Autore:
BOVINGDON ME; WEBSTER RA;
Indirizzi:
UNIV LONDON UNIV COLL,DEPT PHARMACOL,GOWER ST LONDON WC1E 6BT ENGLAND
Titolo Testata:
Journal of chromatography B. Biomedical applications
fascicolo: 1-2, volume: 659, anno: 1994,
pagine: 157 - 183
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; AMINO-ACID-ANALYSIS; PRE-COLUMN DERIVATIZATION; PRECOLUMN FLUORESCENCE DERIVATIZATION; CYCLODEXTRIN BONDED PHASES; HUMAN CEREBROSPINAL-FLUID; CHIRAL STATIONARY PHASE; ELECTROCHEMICAL DETECTION; CARBOXYLIC-ACIDS; 9-FLUORENYLMETHYL CHLOROFORMATE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
106
Recensione:
Indirizzi per estratti:
Citazione:
M.E. Bovingdon e R.A. Webster, "DERIVATIZATION REACTIONS FOR NEUROTRANSMITTERS AND THEIR AUTOMATION", Journal of chromatography B. Biomedical applications, 659(1-2), 1994, pp. 157-183

Abstract

Many reagents suitable for the derivatization of neurotransmitters are selective for the amino function. Others, however, are selective forthe carboxyl-, thiol- and hydroxyl function, and recently, reagents selective for more than one function have been produced. Interest persists in the established reagents, with their well understood behaviour which assists automation of analysis as much as new technology. Workers appear reluctant to tackle the optimization of many novel reagents. Chiral reagents may become important if d-amino acids are shown to be significant from a physiological point of view. Solid-phase reagents offer better regulated chemistry and combined derivatization/solid-phase extraction, which make them an exciting prospect.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 00:53:59