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Titolo:
fMRI of visual system activation in the conscious rabbit
Autore:
Wyrwicz, AM; Chen, NK; Li, LM; Weiss, C; Disterhoft, JF;
Indirizzi:
Northwestern Univ, Ctr MR Res, ENH Res Inst, Evanston, IL 60201 USA Northwestern Univ Evanston IL USA 60201 Res Inst, Evanston, IL 60201 USA Northwestern Univ, Dept Neurobiol & Physiol, Evanston, IL 60201 USA Northwestern Univ Evanston IL USA 60201 & Physiol, Evanston, IL 60201 USA Northwestern Univ, Dept Biomed Engn, Evanston, IL 60201 USA Northwestern Univ Evanston IL USA 60201 omed Engn, Evanston, IL 60201 USA Northwestern Univ, Sch Med, Dept Cell & Mol Biol, Evanston, IL 60201 USA Northwestern Univ Evanston IL USA 60201 Mol Biol, Evanston, IL 60201 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 3, volume: 44, anno: 2000,
pagine: 474 - 478
SICI:
0740-3194(200009)44:3<474:FOVSAI>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
FUNCTIONAL MRI; ANESTHETIZED RATS; BRAIN ACTIVITY; CORTEX; SIGNAL; STIMULATION; MEMORIES;
Keywords:
fMRI; BOLD; conscious animal model; visual cortex; functional activations;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Wyrwicz, AM Northwestern Univ, Ctr MR Res, ENH Res Inst, Res Pk,1033 Univ Pl,Suite 150, Evanston, IL 60201 USA Northwestern Univ Res Pk,1033 Univ Pl,Suite 150 Evanston IL USA 60201
Citazione:
A.M. Wyrwicz et al., "fMRI of visual system activation in the conscious rabbit", MAGN RES M, 44(3), 2000, pp. 474-478

Abstract

A conscious rabbit preparation developed for fMRI, and the results from visual stimulation studies at a 4.7T magnetic field are described. The rabbitis ideal for these experiments because of its natural tolerance for restraint, High spatial and temporal resolution magnetic resonance images, without movement artifacts, were obtained during long periods of restraint. Functional activation in primary visual cortex and lateral geniculate nucleus (LGN) were reproducibly observed in response to light stimulus. In comparisonto existing anesthetized animal models, a functional response free of the anesthetic modulation can be recorded with the new approach. The conscious animal model can be applied to functional studies of sensory systems, learning and memory, and drug-induced cerebral activation. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:29:18