Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Improving outcome over time of percutaneous coronary interventions in unstable angina
Autore:
Singh, M; Rihal, CS; Berger, PB; Bell, MR; Grill, DE; Garratt, KN; Barseness, GW; Holmes, DR;
Indirizzi:
Mayo Clin & Mayo Fdn, Div Cardiovasc Dis & Internal Med, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 Med, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn, Biostat Sect, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 Sect, Rochester, MN 55905 USA
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
fascicolo: 3, volume: 36, anno: 2000,
pagine: 674 - 678
SICI:
0735-1097(200009)36:3<674:IOOTOP>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; ANGIOPLASTY; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Holmes, DR Mayo Clin & Mayo Fdn, Div Cardiovasc Dis & Internal Med, 200 1st St SW, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn 200 1st St SW Rochester MN USA 55905 5 USA
Citazione:
M. Singh et al., "Improving outcome over time of percutaneous coronary interventions in unstable angina", J AM COL C, 36(3), 2000, pp. 674-678

Abstract

OBJECTIVE This study was performed to evaluate the recent changes in the interventions in patients with unstable angina (UA). BACKGROUND An early invasive strategy has not been shown to be superior toconservative treatment in patients with UA. Earlier studies had utilized older technology. Interventional approaches have changed in the recent past,but to our knowledge, no large studies have addressed the impact of these changes on the outcome of coronary interventions. METHODS We analyzed the in-hospital and intermediate-term outcome in 7,632patients with UA who underwent coronary interventions in the last two decades. The study population was divided into three groups: group 1, n = 2,209who had coronary intervention from 1979 to 1989; group 2, n = 2,212 with interventions from 1990 to 1993; and group 3, n = 3,211 treated from 1994 to1998. RESULTS Group 2 and 3 patients were older and sicker compared with group 1patients. The clinical success improved significantly in group 3 (94.1%) compared with group 2 (87%) and group 1 (76.5%) (p < 0.001). There was a significant reduction in in-hospital mortality, Q- wave myocardial infarction and need for emergency bypass surgery in group 3 compared with the earlier groups. One-year event-free survival was also significantly higher in the recent group compared with the earlier groups: 77% in group 3, 70% in group 2 and 74% in group 1 (p < 0.001). With the use of multivariate models to adjust for clinical and angiographic variables, treatment during the most recent era was found to be independently associated with improved in-hospital and intermediate-term outcomes. CONCLUSIONS There has been significant improvement in the in hospital and intermediate-term outcome of coronary interventions in patients with UA in recent years; newer trials comparing conservative and invasive strategies are therefore needed. (J Am Coll Cardiol 2000;36: 674-8) (c) 2000 by the American College of Cardiology

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:18:25