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Titolo:
Role of Doppler US in acute peptic ulcer hemorrhage: Can it predict failure of endoscopic therapy?
Autore:
Wong, RCK; Chak, A; Kobayashi, K; Isenberg, GA; Cooper, GS; Carr-Locke, DL; Sivak, MV;
Indirizzi:
Case Western Reserve Univ, Div Gastroenterol Wearn 247, Univ Hosp Cleveland, Sch Med, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OHUSA 44106 Cleveland, OH 44106 USA Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Gastroenterol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Div Gastroenterol, Boston, MA 02115 USA
Titolo Testata:
GASTROINTESTINAL ENDOSCOPY
fascicolo: 3, volume: 52, anno: 2000,
pagine: 315 - 321
SICI:
0016-5107(200009)52:3<315:RODUIA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
UPPER GASTROINTESTINAL HEMORRHAGE; PROSPECTIVE RANDOMIZED TRIAL; ACTIVELY BLEEDING ULCERS; INJECTION THERAPY; MULTIPOLAR ELECTROCOAGULATION; GASTRODUODENAL ULCERS; ADRENALINE INJECTION; HEAT PROBE; HEMOSTASIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Wong, RCK Case Western Reserve Univ, Div Gastroenterol Wearn 247, Univ Hosp Cleveland, Sch Med, 11100 Euclid Ave, Cleveland, OH 44106 USA Case Western Reserve Univ 11100 Euclid Ave Cleveland OH USA 44106
Citazione:
R.C.K. Wong et al., "Role of Doppler US in acute peptic ulcer hemorrhage: Can it predict failure of endoscopic therapy?", GASTROIN EN, 52(3), 2000, pp. 315-321

Abstract

Background: Recurrent bleeding after successful primary endoscopic hemostasis of acutely bleeding ulcers is a significant problem. This study evaluates endoscopic Doppler ultrasound (US) in assessing risk of recurrent bleeding in patients presenting with acute peptic ulcer hemorrhage,Methods: In this prospective, double-blind, nonrandomized trial, patients were enrolled from a single academic institution. Only patients with endoscopically confirmed gastric, duodenal, pyloric, or anastomotic ulcers were enrolled. The therapeutic endoscopist was blinded to the Doppler US signal from the ulcer and based treatment decisions on standard guidelines, A 16 MHz pulsed-wave, linear scanning, US probe was used through the accessory channel of an endoscope to assess for the presence of a Doppler signal. Results: Fifty-two of 139 screened patients entered the trial (55 Doppler sessions), Endoscopic therapy was performed in 42% (30-day recurrent bleeding rate of 17%), Ulcers that remained persistently Doppler positive immediately after endoscopic therapy had a significantly higher rate of recurrent bleeding than ulcers where the Doppler signal was abolished: 100% versus 11% (p = 0.003). There were no bleeding-related deaths. Conclusions: A persistently positive Doppler US signal appears to be a marker of inadequate endoscopic therapy in patients with acutely bleeding peptic ulcers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:12:31