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Titolo:
Frequency of neuroleptic malignant syndrome in a large psychiatric hospital in Moscow
Autore:
Spivak, B; Maline, DI; Kozyrev, VN; Mester, R; Neduva, SA; Ravilov, RS; Weizman, A;
Indirizzi:
Ness Ziona Mental Hlth Ctr, Res Unit, IL-74100 Ness Ziona, Israel Ness Ziona Mental Hlth Ctr Ness Ziona Israel IL-74100 Ness Ziona, Israel Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 ac Med, IL-69978 Tel Aviv, Israel Moscow Res Inst Psychiat, Dept Intens Therapy, Psychiat Hosp 4, Moscow, Russia Moscow Res Inst Psychiat Moscow Russia Psychiat Hosp 4, Moscow, Russia Moscow Psychiat Hosp 1, Moscow, Russia Moscow Psychiat Hosp 1 Moscow Russia ow Psychiat Hosp 1, Moscow, Russia Geha Psychiat Hosp, Res Unit, Petah Tiqwa, Israel Geha Psychiat Hosp Petah Tiqwa Israel sp, Res Unit, Petah Tiqwa, Israel Felsenstein Med Res Ctr, Lab Biol Psychiat, Petah Tiqwa, Israel Felsenstein Med Res Ctr Petah Tiqwa Israel sychiat, Petah Tiqwa, Israel
Titolo Testata:
EUROPEAN PSYCHIATRY
fascicolo: 5, volume: 15, anno: 2000,
pagine: 330 - 333
SICI:
0924-9338(200008)15:5<330:FONMSI>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
INPATIENTS;
Keywords:
frequency; mortality rate; neuroleptic malignant syndrome; possible risk;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Spivak, B Ness Ziona Mental Hlth Ctr, Res Unit, POB 1, IL-74100 Ness Ziona, Israel Ness Ziona Mental Hlth Ctr POB 1 Ness Ziona Israel IL-74100 ael
Citazione:
B. Spivak et al., "Frequency of neuroleptic malignant syndrome in a large psychiatric hospital in Moscow", EUR PSYCHIA, 15(5), 2000, pp. 330-333

Abstract

A ten-year prospective survey of neuroleptic malignant syndrome (NMS) was performed in a major psychiatric hospital (1,510 beds) in Moscow. All inpatients who developed a persistent and severe extrapyramidal rigidity accompanied by fever after exposure to neuroleptic medication were screened for NMS. The diagnosis of NMS was established according to Levenson's criteria and at a later stage all NMS Gases were reevaluated using the DSM-IV researchcriteria. Data on age, gender and psychiatric diagnoses were analyzed. Of the 78,708 inpatients treated with neuroleptic agents, 19 separate patientshad an episode of NMS, for a frequency of 0.02%. Mortality rate was 10.5% (2/19 patients). Of the three potential risk factors studied, only young age (less than or equal to 25 years) was significantly associated with an increased frequency of NMS (P < 0.01). The low rate of NMS found here comparedto studies in other countries may be due to the stringent demands for NMS diagnosis. More large-scale prospective studies including detailed clinicaland laboratory data are needed to clarify these differences and their impact on the prevalence and risk factors of NMS. (C) 2000 Editions scientifiques et medicales.

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Documento generato il 03/04/20 alle ore 07:30:07