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Titolo:
Improvement of brain perfusion SPET using iterative reconstruction with scatter and non-uniform attenuation correction
Autore:
Kauppinen, T; Koskinen, MO; Alenius, S; Vanninen, E; Kuikka, JT;
Indirizzi:
Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, Kuopio 70211, Finland Kuopio Univ Hosp Kuopio Finland 70211 & Nucl Med, Kuopio 70211, Finland Univ Kuopio, FIN-70211 Kuopio, Finland Univ Kuopio Kuopio Finland FIN-70211 v Kuopio, FIN-70211 Kuopio, Finland Tampere Univ Hosp, Dept Clin Physiol & Nucl Med, Tampere, Finland Tampere Univ Hosp Tampere Finland Physiol & Nucl Med, Tampere, Finland Tampere Univ Technol, Signal Proc Lab, FIN-33101 Tampere, Finland Tampere Univ Technol Tampere Finland FIN-33101 IN-33101 Tampere, Finland
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 9, volume: 27, anno: 2000,
pagine: 1380 - 1386
SICI:
0340-6997(200009)27:9<1380:IOBPSU>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
BAYESIAN IMAGE-RECONSTRUCTION; MEDIAN ROOT PRIOR; EMISSION TOMOGRAPHY; TRANSMISSION DATA; ORDERED SUBSETS; SINGLE ISOTOPE; SUBTRACTION; ALGORITHMS; PET;
Keywords:
brain perfusion; iterative reconstruction; non-uniform attenuation correction; single-photon emission tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Kauppinen, T Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, POB 1777, Kuopio 70211, Finland Kuopio Univ Hosp POB 1777 Kuopio Finland 70211 0211, Finland
Citazione:
T. Kauppinen et al., "Improvement of brain perfusion SPET using iterative reconstruction with scatter and non-uniform attenuation correction", EUR J NUCL, 27(9), 2000, pp. 1380-1386

Abstract

Filtered back-projection (FBP) is generally used as the reconstruction method for single-photon emission tomography although it produces noisy imageswith apparent streak artefacts. It is possible to improve the image quality by using an algorithm with iterative correction steps. The iterative reconstruction technique also has an additional benefit in that computation of attenuation correction can be included in the process. A commonly used iterative method, maximum-likelihood expectation maximisation (ML-EM), can be accelerated using ordered subsets (OS-EM). We have applied to the OS-EM algorithm a Bayesian one-step late correction method utilising median root prior (MRP). Methodological comparison was per formed by means of measurements obtained with a brain perfusion phantom and using patient data. The aim of this work was to quantitate the accuracy of iterative reconstruction with scatter and non-uniform attenuation corrections and post-filtering in SPET brain perfusion imaging. SPET imaging was performed using a triple-head gamma camera with fan-beam collimators, Transmission and emission scans were acquired simultaneously. The brain phantom used was a high-resolution three-dimensional anthropomorphic JB003 phantom. Patient studies were performed inten chronic pain syndrome patients. The images were reconstructed using conventional FBP and iterative OS-EM and MRP techniques including scatter andnonuniform attenuation corrections. Iterative reconstructions were individually post-filtered. The quantitative results obtained with the brain perfusion phantom were compared with the known actual contrast ratios. The calculated difference from the true values was largest with the FBP method; iteratively reconstructed images proved closer to the reality. Similar findingswere obtained in the patient studies. The plain OS-FM method improved the contrast whereas in the case of the MRP technique the improvement in contrast was not so evident with post-filtering.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 17:28:21