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Titolo:
Parental consumption of contaminated sport fish from Lake Ontario and predicted fecundability
Autore:
Buck, GM; Vena, JE; Schisterman, EF; Dmochowski, J; Mendola, P; Sever, LE; Fitzgerald, E; Kostyniak, P; Greizerstein, H; Olson, J;
Indirizzi:
SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY 14214 USA SUNY Buffalo Buffalo NY USA 14214 al & Prevent Med, Buffalo, NY 14214 USA SUNY Buffalo, Div Biostat, Buffalo, NY 14214 USA SUNY Buffalo Buffalo NY USA 14214 alo, Div Biostat, Buffalo, NY 14214 USA Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA Harvard Univ Cambridge MA USA 02138 pt Epidemiol, Cambridge, MA 02138 USA US EPA, Natl Hlth & Environm Effects Res Lab, Res Triangle Pk, NC 27711 USA US EPA Res Triangle Pk NC USA 27711 es Lab, Res Triangle Pk, NC 27711 USA Univ Texas, Sch Publ Hlth, Houston, TX USA Univ Texas Houston TX USAUniv Texas, Sch Publ Hlth, Houston, TX USA Bur Environm & Occupat Epidemiol, New York State Dept Hlth, Buffalo, NY USA Bur Environm & Occupat Epidemiol Buffalo NY USA pt Hlth, Buffalo, NY USA SUNY Buffalo, Dept Pharmacol & Toxicol, Buffalo, NY 14214 USA SUNY Buffalo Buffalo NY USA 14214 rmacol & Toxicol, Buffalo, NY 14214 USA SUNY Buffalo, Dept Clin Lab Sci, Buffalo, NY 14214 USA SUNY Buffalo Buffalo NY USA 14214 ept Clin Lab Sci, Buffalo, NY 14214 USA
Titolo Testata:
EPIDEMIOLOGY
fascicolo: 4, volume: 11, anno: 2000,
pagine: 388 - 393
SICI:
1044-3983(200007)11:4<388:PCOCSF>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYCHLORINATED-BIPHENYLS PCBS; TIME-TO-PREGNANCY; LONG-TERM RECALL; ORGANOCHLORINE COMPOUNDS; OVULATORY INFERTILITY; PESTICIDE EXPOSURE; ANGLER COHORT; HUMAN HEALTH; BODY-MASS; QUESTIONNAIRE;
Keywords:
angler; fecundability; fish consumption; polychlorinated biphenyls; pregnancy; reproduction; toxicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: Buck, GM SUNY Buffalo, Dept Social & Prevent Med, 270 Farber Hall,3435 Main St, Buffalo, NY 14214 USA SUNY Buffalo 270 Farber Hall,3435 Main St Buffalo NY USA 14214 SA
Citazione:
G.M. Buck et al., "Parental consumption of contaminated sport fish from Lake Ontario and predicted fecundability", EPIDEMIOLOG, 11(4), 2000, pp. 388-393

Abstract

Wildlife studies suggest that consumption of contaminated fish from the Great Lakes may expose humans to polychlorinated biphenyls and persistent chlorinated pesticides. To assess whether, time to pregnancy or fecundability is affected, we conducted a telephone survey in 1993 with female members ofthe New York State Angler Cohort Study who were considering pregnancy between 1991 and 1994 (N = 2,445). Among the 1,234 (50%) women who became pregnant, 895 (73%) had a known time to pregnancy. Upon enrollment into the cohort in 1991, both partners reported duration and frequency of Lake Ontario spore fish consumption. We estimated lifetime exposure to polychlorinated biphenyls from recent consumption and used a discrete time analog of Cox proportional hazards analysis to estimate conditional fecundability ratios and 95% confidence intervals (CIs) for fish consumption among couples with complete exposure data who discontinued birth control to become pregnant (N = 575). Maternal consumption of fish for 3-6 years was associated with reducedfecundability (fecundability ratio = 0.75; 95% CI = 0.59-0.91), as was more than a monthly fish meal in 1991 (fecundability ratio = 0.73; 95% CI = 0.54-0.98). Our findings suggest that maternal but not paternal consumption of contaminated fish may reduce fecundability among couples attempting pregnancy.

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Documento generato il 12/07/20 alle ore 06:45:09