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Titolo:
Diagnostic accuracy of helical CT arterial portography and CT hepatic arteriography for hypervascular hepatocellular carcinoma in chronic liver damage - An ROC analysis
Autore:
Makita, O; Yamashita, Y; Arakawa, A; Nakayama, Y; Mitsuzaki, K; Ando, M; Namimoto, T; Takahashi, M;
Indirizzi:
Kumamoto Univ, Sch Med, Dept Radiol, Kumamoto 8608556, Japan Kumamoto Univ Kumamoto Japan 8608556 ept Radiol, Kumamoto 8608556, Japan
Titolo Testata:
ACTA RADIOLOGICA
fascicolo: 5, volume: 41, anno: 2000,
pagine: 464 - 469
SICI:
0284-1851(200009)41:5<464:DAOHCA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
PORTAL PERFUSION; DEFECTS; PSEUDOLESIONS; ANGIOGRAPHY; CIRRHOSIS; TUMORS;
Keywords:
hepatocellular carcinoma, CT; CT arterial portography; CT hepatic arteriography; receiver operating characteristics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Makita, O Kumamoto Univ, Sch Med, Dept Radiol, 1-1-1 Honjo, Kumamoto 8608556, Japan Kumamoto Univ 1-1-1 Honjo Kumamoto Japan 8608556 8608556, Japan
Citazione:
O. Makita et al., "Diagnostic accuracy of helical CT arterial portography and CT hepatic arteriography for hypervascular hepatocellular carcinoma in chronic liver damage - An ROC analysis", ACT RADIOL, 41(5), 2000, pp. 464-469

Abstract

Purpose: To evaluate the detectability of hypervascular hepatocellular carcinomas (HCCs) in chronic liver damage with helical CT arterial portography(CTAP) and CT hepatic arteriography (CTHA). Material and Methods: Thirty-nine HCC patients who underwent CTAP and CTHAwere studied. Diagnostic abilities of CTAP alone, CTHA alone, or combined CTAP and CTHA were evaluated by receiver operating characteristic (ROC) analysis. Fifty-three images with 53 HCC nodules were evaluated. Tumor size ranged from 5 to 90 mm (mean 22.8 mm). Sensitivities and specificities for all techniques were calculated. Results: ROC analysis showed the diagnostic ability significantly better with combined CTAP and CTHA (mean area under the ROC curve (Az)=0.95), or CTHA alone (Az=0.93) than CTAP alone (Az=0.87) (p<0.01). Combined CTAP and CTHA showed the best sensitivity (95.0%), followed by CTHA alone (88.1%) and CTAP alone (85.5%). The specificities of all three imaging techniques were relatively low (54.1% for combined CTAP and CTHA, 71.1% for CTHA alone, and54.1% for CTAP alone) because of perfusion abnormalities of the liver parenchyma. Conclusion. The combination of CTAP and CTHA is superior to CTAP alone fordetection of hypervascular HCCs. However, its specificity was relatively low in chronic liver damage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:29:52