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Titolo:
Elastic pressure-volume curves indicate derecruitment after a single deep expiration in anaesthetised and muscle-relaxed healthy man
Autore:
Sigurdsson, S; Svantesson, C; Larsson, A; Jonson, B;
Indirizzi:
Univ Lund Hosp, Dept Anaesthesia & Intens Care, SE-22185 Lund, Sweden UnivLund Hosp Lund Sweden SE-22185 & Intens Care, SE-22185 Lund, Sweden Univ Lund Hosp, Dept Clin Physiol, SE-22185 Lund, Sweden Univ Lund Hosp Lund Sweden SE-22185 Clin Physiol, SE-22185 Lund, Sweden Gentofte Univ Hosp, Dept Anaesthesiol, Gentofte, Denmark Gentofte Univ Hosp Gentofte Denmark ept Anaesthesiol, Gentofte, Denmark
Titolo Testata:
ACTA ANAESTHESIOLOGICA SCANDINAVICA
fascicolo: 8, volume: 44, anno: 2000,
pagine: 980 - 984
SICI:
0001-5172(200009)44:8<980:EPCIDA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY SYSTEM; GENERAL-ANESTHESIA; AIRWAY-CLOSURE; ATELECTASIS; RECRUITMENT; REEXPANSION; SURFACTANT; MODEL;
Keywords:
pressure-volume relations; anesthesia; muscle relaxation;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Sigurdsson, S Univ Lund Hosp, Dept Anaesthesia & Intens Care, SE-22185 Lund, Sweden Univ Lund Hosp Lund Sweden SE-22185 SE-22185 Lund, Sweden
Citazione:
S. Sigurdsson et al., "Elastic pressure-volume curves indicate derecruitment after a single deep expiration in anaesthetised and muscle-relaxed healthy man", ACT ANAE SC, 44(8), 2000, pp. 980-984

Abstract

Background: in acute respiratory distress syndrome, lung volume is lost immediately after positive end-expiratory pressure (PEEP) is removed and is not immediately regained when PEEP is restored to its original value. The aim of this study was to investigate whether the same phenomenon also occurs in cardiopulmonary healthy individuals during anaesthesia and muscle relaxation. Methods: In 13 anaesthetised and muscle-relaxed patients, inspiratory elastic pressure-volume (P-el-V) curves were, after lung recruitment, obtained from zero end-expiratory airway pressure (ZEEP) and from a PEEP of 5 cmH(2)O. The curves were aligned on a common volume axis. Differences in lung volumes and compliance (C-rs) were calculated at the different airway pressures. Results: At comparable pressures the ZEEP curve showed significantly lowervolumes up to an airway pressure of 25 cmH(2)O. Maximum C-rs was similar on the curves obtained from ZEEP and PEEP However, the lower segments of thecurve recorded from PEEP showed lower C-rs compared to the curve recorded from ZEEPConclusion: During anaesthesia and muscle paralysis, the P-el-IV relationschange immediately when 5 cmH(2)O of PEEP is removed. This phenomenon is probably mainly caused by closure of small airways and only in a minor part,if any, by formation of atelectasis. This study indicates that under theseconditions lung volume might easily be normalised by a large breath producing an airway pressure of 20 cmH(2)O.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 07:11:36