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Titolo:
Temporal lobe volume in panic disorder - a quantitative magnetic resonanceimaging study
Autore:
Vythilingam, M; Anderson, ER; Goddard, A; Woods, SW; Staib, LH; Charney, DS; Bremner, JD;
Indirizzi:
Yale Univ, Sch Med, Yale Psychiat Inst Res, Dept Radiol, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 es, Dept Radiol, New Haven, CT 06520 USA Yale Univ, Sch Med, Yale Psychiat Inst Res, Dept Psychiat, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 , Dept Psychiat, New Haven, CT 06520 USA
Titolo Testata:
PSYCHIATRY RESEARCH-NEUROIMAGING
fascicolo: 2, volume: 99, anno: 2000,
pagine: 75 - 82
SICI:
0925-4927(20000828)99:2<75:TLVIPD>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTTRAUMATIC-STRESS-DISORDER; HIPPOCAMPAL VOLUME; SEXUAL ABUSE; ABNORMALITIES; ANXIETY; MRI; EPILEPSY; ATTACKS; EEG;
Keywords:
panic disorder; magnetic resonance imaging; morphometry; limbic system; temporal lobe volume;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Bremner, JD Yale Univ, Sch Med, Yale Psychiat Inst Res, Dept Radiol, 184 Liberty St, New Haven, CT 06520 USA Yale Univ 184 Liberty St New Haven CT USA 06520 , CT 06520 USA
Citazione:
M. Vythilingam et al., "Temporal lobe volume in panic disorder - a quantitative magnetic resonanceimaging study", PSYCH RES-N, 99(2), 2000, pp. 75-82

Abstract

Although previous studies have used magnetic resonance imaging (MRI) to demonstrate qualitative abnormalities of the temporal lobes in patients with panic disorder, no study to date has applied quantitative volumetric methods to evaluate brain changes in panic disorder. The purpose of this study was to measure the volume of the temporal lobe and the hippocampus in patients with panic disorder and healthy control subjects using quantitative MRI measures. The volume of the temporal lobe, hippocampus and whole brain was measured in 14 patients with panic disorder and 13 healthy subjects. The mean volume of the left and right temporal lobes was significantly smaller in panic disorder compared to healthy subjects (16 770 +/- 909 mm(3) vs. 18 343 +/- 1740 mm(3)). This result was significant after controlling for differences in whole brain volume. There was no significant difference in volume of the hippocampus between patients and control subjects. These findings are consistent with smaller temporal lobe volume in panic disorder despite normal hippocampal volume. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:07:11