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Titolo:
Prevalence and duration of postmenopausal hormone replacement therapy use in a managed care organization, 1990-1995
Autore:
Connelly, MT; Richardson, M; Platt, R;
Indirizzi:
Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA 02215 USA Harvard Univ Boston MA USA 02215 ory Care & Prevent, Boston, MA 02215 USA Harvard Pilgrim Hlth Care, Boston, MA 02215 USA Harvard Pilgrim Hlth CareBoston MA USA 02215 Care, Boston, MA 02215 USA Harvard Univ, Sch Med, Beth Israel Hosp, Dept Obstet & Gynecol, Boston, MAUSA Harvard Univ Boston MA USA el Hosp, Dept Obstet & Gynecol, Boston, MAUSA Harvard Vanguard Menopause Consultat Serv, Boston, MA USA Harvard VanguardMenopause Consultat Serv Boston MA USA , Boston, MA USA Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Med,Channing Lab, Boston, MA USA Harvard Univ Boston MA USA s Hosp, Dept Med,Channing Lab, Boston, MA USA
Titolo Testata:
JOURNAL OF GENERAL INTERNAL MEDICINE
fascicolo: 8, volume: 15, anno: 2000,
pagine: 542 - 550
SICI:
0884-8734(200008)15:8<542:PADOPH>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROGEN REPLACEMENT; UNITED-STATES; OLDER WOMEN; CARDIOVASCULAR-DISEASE; AFRICAN-AMERICAN; RANDOMIZED TRIAL; COMMUNITY SURVEY; ELDERLY WOMEN; BONE-DENSITY; DANISH WOMEN;
Keywords:
menopause; hormone replacement therapy; estrogen; adherence; prevalence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
63
Recensione:
Indirizzi per estratti:
Indirizzo: Connelly, MT Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, 126 Brookline Ave,Suite 203, Boston, MA 02215 USA Harvard Univ 126 Brookline Ave,Suite 203 Boston MA USA 02215
Citazione:
M.T. Connelly et al., "Prevalence and duration of postmenopausal hormone replacement therapy use in a managed care organization, 1990-1995", J GEN INT M, 15(8), 2000, pp. 542-550

Abstract

OBJECTIVE: To determine the prevalence and duration of postmenopausal hormone replacement therapy (HRT) use and identify correlates of adherence to therapy. DESIGN: Population-based cohort study. SETTING: Staff-model health maintenance organization. PARTICIPANTS: Female members, 40 years and older. MEASUREMENTS AND MAIN RESULTS: Prevalence and duration of use were measured between 1990 and 1995. Duration was assessed by Kaplan-Meier and proportional hazards methods. Hormone replacement therapy use increased from 10.3% in 1990 to 20.7% in 1995. Greatest use (24%) occurred among menopausal women age 50 to 54 years. Less than 5% of women 75 and older used HRT. Among 1,680 first-time recipients of HRT, two thirds of initial prescriptions were written by internists. Thirty-eight percent discontinued HRT within 1 year. For the subset whose indication for therapy was ascertained, prevention ofchronic disease was associated with a 33% 1-year discontinuation rate. Factors associated with longer duration of therapy included white race (relative risk [RR], 1.63; 95% confidence interval [95% CI], 1.32 to 2.02), younger age (RR, 1.02 per year; 95% CI 1.01 to 1.03), and changing the preparation or dose of estrogen (RR, 5.62; 95% CI, 4.33 to 7.25). The formulation (esterified estrogens 0.625 mg versus conjugated estrogens 0.625 mg) was also associated with greater duration of use; all other estrogens were, as a group, associated with shorter duration of use. Those who received their initial HRT prescription from an internist were more likely to continue therapy than those who received it from a gynecologist. CONCLUSIONS: Despite increased use of HRT, only a minority of women in this population used HRT, and many of those discontinued therapy within 1 year.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 01:31:28