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Titolo:
Toxicity of ingested formalin and its management
Autore:
Pandey, CK; Agarwal, A; Baronia, A; Singh, N;
Indirizzi:
Sanjay Gandhi Postgrad Inst Med Sci, Dept Anaesthesiol & Crit Care Med, Lucknow 226014, Uttar Pradesh, India Sanjay Gandhi Postgrad Inst Med Sci Lucknow Uttar Pradesh India 226014 ia
Titolo Testata:
HUMAN & EXPERIMENTAL TOXICOLOGY
fascicolo: 6, volume: 19, anno: 2000,
pagine: 360 - 366
SICI:
0960-3271(200006)19:6<360:TOIFAI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMORRHAGIC RADIATION PROCTITIS; FORMALDEHYDE; INSTILLATION; METABOLISM; METHANOL; THERAPY;
Keywords:
formaldehyde; formalin; methanol; formic acid; ingestion; toxicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Pandey, CK Sanjay Gandhi Postgrad Inst Med Sci, Dept Anaesthesiol & Crit Care Med, Lucknow 226014, Uttar Pradesh, India Sanjay Gandhi Postgrad Inst Med Sci Lucknow Uttar Pradesh India 226014
Citazione:
C.K. Pandey et al., "Toxicity of ingested formalin and its management", HUM EXP TOX, 19(6), 2000, pp. 360-366

Abstract

Formaldehyde is a physiological intermediary metabolite taking part in many biological process in the body. It is a constituent of many items of daily use, including foods. It is also used in medicine for treatment of some conditions. A 40% solution of formaldehyde in water is known as formalin. Formalin is irritating, corrosive and toxic and absorbed from all surfaces ofthe body. Ingestion is rare because of alarming odour and irritant effect but documented in accidental, homicidal or suicidal attempts. Ingestion canlead to immediate deleterious effects on almost all systems of the body including gastrointestinal tract, central nervous system, cardiovascular system and hepato-renal system, causing gastrointestinal hemorrhage, cardiovascular collapse, unconsciousness or convulsions, severe metabolic acidosis and acute respiratory distress syndrome. No specific antidote is available. Treatment of toxicity is supportive care of the various organ systems. Multidisciplinary approach is required for proper management.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 05:25:16