Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
APATITE DEPOSITION ON TITANIUM SURFACES - THE ROLE OF ALBUMIN ADSORPTION
Autore:
SERRO AP; FERNANDES AC; SARAMAGO B; LIMA J; BARBOSA MA;
Indirizzi:
INST SUPER TECN,CTR QUIM ESTRUTURAL,COMPLEXO I,AV ROVISCO PAIS P-1096LISBON PORTUGAL UNIV OPORTO,FAC ENGN,INST BIOMED ENGN P-4150 OPORTO PORTUGAL
Titolo Testata:
Biomaterials
fascicolo: 14, volume: 18, anno: 1997,
pagine: 963 - 968
SICI:
0142-9612(1997)18:14<963:ADOTS->2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DROP SHAPE-ANALYSIS; CONTACT ANGLES; FREE-ENERGIES; POLYMERS; SILICA;
Keywords:
TITANIUM; ALBUMIN ADSORPTION; APATITE DEPOSITION; WETTABILITY; ELECTROCHEMICAL IMPEDANCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
A.P. Serro et al., "APATITE DEPOSITION ON TITANIUM SURFACES - THE ROLE OF ALBUMIN ADSORPTION", Biomaterials, 18(14), 1997, pp. 963-968

Abstract

Titanium implant surfaces are known to spontaneously nucleate apatitelayers when in contact with simulated body fluids. However, adsorption of proteins may influence the process of apatite layer formation. Inthis study the role of bovine serum albumin (BSA) adsorption in the process of apatite deposition on titanium substrates is investigated. Deposition of calcium phosphate was induced by immersing titanium substrates in a Hank's balanced salt solution (HBSS) for times ranging from1 to 23 days. The resulting substrates were studied by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS), wettability measurements and electrochemical impedance determinations. All these methods indicate the presenceof a calcium phosphate layer. The same procedure was repeated substituting HBSS with a solution of BSA in HBSS. Although SEM, EDS and electrochemical impedance spectra do not reveal the presence of an apatite layer, XPS analysis strongly indicates that the inhibition of apatite formation by BSA is only partial. The competition between BSA adsorption and apatite deposition seems to lead to a mixed film where the protein co-exists with calcium phosphate. Wettability studies suggest thatthis surface film is heterogeneous and porous, similar to the thickerfilms formed in albumin-free HBSS. (C) 1997 Elsevier Science Limited. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 21:55:04