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Titolo:
Characterization of gyrA mutations associated with fluoroquinolone resistance in Campylobacter coli by DNA sequence analysis and MAMA PCR
Autore:
Zirnstein, G; Helsel, L; Li, Y; Swaminathan, B; Besser, J;
Indirizzi:
Ctr Dis Control & Prevent, Natl Ctr Infect Dis, US PHS, US Dept HHS, Atlanta, GA 30333 USA Ctr Dis Control & Prevent Atlanta GA USA 30333 HHS, Atlanta, GA 30333 USA Minnesota Dept Hlth, Minneapolis, MN USA Minnesota Dept Hlth Minneapolis MN USA ta Dept Hlth, Minneapolis, MN USA
Titolo Testata:
FEMS MICROBIOLOGY LETTERS
fascicolo: 1, volume: 190, anno: 2000,
pagine: 1 - 7
SICI:
0378-1097(20000901)190:1<1:COGMAW>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
QUINOLONE RESISTANCE; CIPROFLOXACIN RESISTANCE; ESCHERICHIA-COLI; JEJUNI GYRA; GENE; IDENTIFICATION; NORFLOXACIN; INFECTIONS; TRAVELERS;
Keywords:
Campylobacter coli; ciprofloxacin resistance; mismatch polymerase chain reaction; gyrA mutation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Zirnstein, G Ctr Dis Control & Prevent, Natl Ctr Infect Dis, US PHS, US Dept HHS, Mail Stop C03,1600 Clifton Rd, Atlanta, GA 30333 USA Ctr Dis Control & Prevent Mail Stop C03,1600 Clifton Rd Atlanta GA USA 30333
Citazione:
G. Zirnstein et al., "Characterization of gyrA mutations associated with fluoroquinolone resistance in Campylobacter coli by DNA sequence analysis and MAMA PCR", FEMS MICROB, 190(1), 2000, pp. 1-7

Abstract

Increasing numbers of fluoroquinolone-resistant Campylobacter ter coli isolates received at the Minnesota State Public Health Laboratory and at the Centers for Disease Control and Prevention have been a cause for concern. The gyrA quinolone resistance-determining regions of several fluoroquinolone-resistant isolates were sequenced to examine the mechanism of resistance. Ciprofloxacin-resistant C. coli isolates examined by DNA sequencing had a Thr-86 to Ile (ACT --> ATT) gyrA mutation, leading to resistance to fluoroquinolone antibiotics. A mismatch amplification mutation assay polymerase chain reaction protocol was developed to detect this gyrA mutation. (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 15:40:24