Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Chronic alcohol exposure and lactation - Extended observations
Autore:
Heil, SH; Subramanian, MG;
Indirizzi:
Wayne State Univ, Sch Med, Dept Obstet & Gynecol, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 et & Gynecol, Detroit, MI 48201 USA
Titolo Testata:
ALCOHOL
fascicolo: 2, volume: 21, anno: 2000,
pagine: 127 - 132
SICI:
0741-8329(200006)21:2<127:CAEAL->2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUCKLING-INDUCED PROLACTIN; MAMMARY-GLAND; RATS; ETHANOL; BEHAVIOR; PATTERNS; RELEASE; MILK;
Keywords:
alcohol; lactation; rats; prolactin; suckling; growth; milk secretion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Heil, SH Univ Vermont, Dept Psychiat, Human Behav Pharmacol Lab, 38 Fletcher Pl, Burlington, VT 05401 USA Univ Vermont 38 Fletcher Pl Burlington VT USA 05401 VT 05401 USA
Citazione:
S.H. Heil e M.G. Subramanian, "Chronic alcohol exposure and lactation - Extended observations", ALCOHOL, 21(2), 2000, pp. 127-132

Abstract

Previous results from our laboratory have indicated that chronic (8 days) alcohol administration inhibits suckling-induced prolactin (PRL) release inresponse to 30 min of suckling. In addition, chronic alcohol administration to dams resulted in growth retardation of their litters. The present study was done to examine how an extended period of suckling (120 min) affectedsuckling-induced PRL release after chronic alcohol exposure. In addition, it was also examined whether the growth retardation observed during alcoholexposure persisted after alcohol infusions were discontinued. Dams were implanted with an atrial catheter on day 3 of lactation and saline or alcohol(1.0- or 2.0-g/kg BW) was administered daily for 8 days (lactation days 5 through 12). Following administration of the initial alcohol dose, the infusion was continued at rates required to maintain blood alcohol levels (BALs) for 4 h each day. Testing took place on day 12. As previously reported, suckling-induced PRL release was inhibited in dams receiving 2.0-g/kg alcohol after 30 min of suckling. However, after 120 min of suckling, PRL releasein these dams was much higher than in either control or 1.0-g/kg alcohol dams. In addition, while the body weights of litters of darns administered 2.0-g/kg alcohol were reduced compared to litters of dams in the other two groups on days 8-16, their body weights rebounded and were not different from the other litters on days 18 or 20. (C) 2000 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 22:00:20