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Titolo:
A prospective population-based study of menopausal symptoms
Autore:
Dennerstein, L; Dudley, EC; Hopper, JL; Guthrie, JR; Burger, HG;
Indirizzi:
Univ Melbourne, Ctr Genet Epidemiol, Dept Psychiat, Off Gender & Hlth, Parkville, Vic 3050, Australia Univ Melbourne Parkville Vic Australia 3050 arkville, Vic 3050, Australia Monash Med Ctr, Prince Henrys Inst Med Res, Clayton, Vic 3168, Australia Monash Med Ctr Clayton Vic Australia 3168 s, Clayton, Vic 3168, Australia
Titolo Testata:
OBSTETRICS AND GYNECOLOGY
fascicolo: 3, volume: 96, anno: 2000,
pagine: 351 - 358
SICI:
0029-7844(200009)96:3<351:APPSOM>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE-AGED WOMEN; MIDLIFE WOMEN; ESTROGEN THERAPY; TRANSITION; SAMPLE; MOOD; DEPRESSION; ESTRADIOL; HORMONES; HEALTH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Dennerstein, L Univ Melbourne, Royal Melbourne Hosp, Dept Psychiat, Off Gender & Hlth, Charles Connibere Bldg, Parkville, Vic 3050, Australia Univ Melbourne Charles Connibere Bldg Parkville Vic Australia 3050
Citazione:
L. Dennerstein et al., "A prospective population-based study of menopausal symptoms", OBSTET GYN, 96(3), 2000, pp. 351-358

Abstract

Objective: To identify symptoms that change in prevalence and severity during midlife and evaluate their relationships to menopausal status, hormonallevels, and other factors. Methods: In a longitudinal, population-based study of 438 Australian-born women observed for 7 years with an 89% retention rate, 172 advanced from premenopause to perimenopause or postmenopause. Annual measures included a 33-item symptom check list; psychosocial, lifestyle, and health-related factors; menstrual status; hormone usage; and blood levels of follicle-stimulating hormone and estradiol (E2). Results: Increasing from early to late perimenopause were the number of women who reported five or more symptoms (+14%), hot flushes (+27%), night sweats (+17%) and vaginal dryness (+17%) (all P < .05). Breast soreness-tenderness decreased with the menopausal transition (-21%). Trouble sleeping increased by +6%. The major change in prevalence was from early to late perimenopause, except for insomnia, which showed a gradual increase. Those variables most related to onset of hot flushes were number of symptoms at early perimenopause (P < .05), having an unskilled or no occupation (P < .05), more than 10 pack-years of smoking (P < .01), and decreased E2 (P < .01). The onset of night sweats increased with the change in E2 (P < .05). The onset of vaginal dryness decreased with more years of education (P < .05). Trouble sleeping was predicted by prior lower well-being (P < .01), belief at baseline that women with many interests hardly notice menopause (P < .01), andhot flushes (P < .01). Conclusion: Although middle-aged women are highly symptomatic, the symptoms that appear to be specifically related to hormonal changes of menopausal transition are vasomotor symptoms, vaginal dryness, and breast tenderness. Insomnia reflected bothersome hot flushes and psychosocial factors. (ObstetGynecol 2000;96:351-8. (C) 2000 by The American College of Obstetricians and Gynecologists).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 17:53:49