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Titolo:
Is akathisia associated with poor clinical response to antipsychotics during acute hospital treatment?
Autore:
Luthra, V; Pinninti, NR; Yoder, K; Musthaq, MS; Umapathy, C; Levinson, DF;
Indirizzi:
Med Coll Penn & Hahnemann Univ, Sch Med, Dept Psychiat, Philadelphia, PA 19102 USA Med Coll Penn & Hahnemann Univ Philadelphia PA USA 19102 ia, PA 19102 USA
Titolo Testata:
GENERAL HOSPITAL PSYCHIATRY
fascicolo: 4, volume: 22, anno: 2000,
pagine: 276 - 280
SICI:
0163-8343(200007/08)22:4<276:IAAWPC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC-INDUCED AKATHISIA; LOW SERUM IRON; DRUG-INDUCED AKATHISIA; SCHIZOPHRENIC-PATIENTS; PLASMA-LEVELS; FLUPHENAZINE; HALOPERIDOL; PSYCHOPATHOLOGY; PREDICTORS; FERRITIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Levinson, DF Univ Penn, Dept Psychiat, 3600 Market St,Room 701, Philadelphia, PA 19104 USA Univ Penn 3600 Market St,Room 701 Philadelphia PA USA 19104 A
Citazione:
V. Luthra et al., "Is akathisia associated with poor clinical response to antipsychotics during acute hospital treatment?", GEN HOSP PS, 22(4), 2000, pp. 276-280

Abstract

Previous studies have suggested that akathisia is associated with poor acute clinical response to antipsychotics and that low serum iron levels are associated with emergence of akathisia. To examine these relationships during routine clinical treatment, we studied patients with DSM-IV schizophreniaor schizoaffective disorder undergoing hospital treatment for acute psychotic exacerbations with doctor's choice medications. There were 34 subjects observed for at least 2 weeks. They were assessed at baseline and weekly byone rater with the Anchored Brief Psychiatric Rating Scale and by another rater with the Barnes Rating Scale for akathisia, with the two raters blindto each other's ratings. Serum ferritin and transferrin levels were obtained at baseline. Seventeen subjects developed akathisia. Subjects with and without akathisia did not differ in change in thinking disturbance or anxiety-depression scares over 2 weeks, or in serum ferritin or transferrin levels. We conclude that mild akathisia by itself is not strongly associated with initial response to low to moderate doses of antipsychotics in the acute clinical setting. Limitations of the study are discussed. (C) 2000 ElsevierScience Inc.

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Documento generato il 23/01/20 alle ore 06:20:57