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Titolo:
Current evidence for the use of paediatric antiretroviral therapy - a PENTA analysis
Autore:
Sharland, M; Gibb, D; Giaquinto, C;
Indirizzi:
St George Hosp, Paediat Infect Dis Unit, London SW17 0QT, England St George Hosp London England SW17 0QT is Unit, London SW17 0QT, England MRC, Clin Trials Unit, London, England MRC London EnglandMRC, Clin Trials Unit, London, England Univ Padua, Padua, Italy Univ Padua Padua ItalyUniv Padua, Padua, Italy
Titolo Testata:
EUROPEAN JOURNAL OF PEDIATRICS
fascicolo: 9, volume: 159, anno: 2000,
pagine: 649 - 656
SICI:
0340-6199(200009)159:9<649:CEFTUO>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS TYPE-1; HIV-1-INFECTED CHILDREN; INFECTION; HIV-1; ZIDOVUDINE; DIDANOSINE; INFANTS; MORTALITY; TRIAL; RNA;
Keywords:
antiretroviral therapy; children; AIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Sharland, M St George Hosp, Paediat Infect Dis Unit, Blackshaw Rd, London SW17 0QT, England St George Hosp Blackshaw Rd London England SW17 0QT , England
Citazione:
M. Sharland et al., "Current evidence for the use of paediatric antiretroviral therapy - a PENTA analysis", EUR J PED, 159(9), 2000, pp. 649-656

Abstract

The introduction of combination antiretroviral therapy has been associatedwith a dramatic clinical improvement in children with human immunodeficiency virus infection. However, the uptake of antiretroviral therapy has been variable across Europe. The Paediatric European Network for the Treatment of AIDS Steering Committee has performed a systematic literature review of paediatric antiretroviral therapy trials. An analysis of the evidence base for the commencement and maintenance of antiretroviral therapy was produced. Suggestions for when to commence antiretroviral therapy, which drugs to start with and how to monitor and sequence drug regimens are given. Conclusion The aim of these guidelines is to help in obtaining equity of access to a uniformly high standard of care for children with human immunodeficiency virus infection in all European countries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 22:30:17