Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Redox signaling: globalization of gene expression
Autore:
Oh, JI; Kaplan, S;
Indirizzi:
Univ Texas, Hlth Sci Ctr, Dept Microbiol & Mol Genet, Sch Med, Houston, TX77030 USA Univ Texas Houston TX USA 77030 Mol Genet, Sch Med, Houston, TX77030 USA
Titolo Testata:
EMBO JOURNAL
fascicolo: 16, volume: 19, anno: 2000,
pagine: 4237 - 4247
SICI:
0261-4189(20000815)19:16<4237:RSGOGE>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYTOCHROME-C-OXIDASE; RHODOBACTER-SPHAEROIDES 2.4.1(T); GRAM-NEGATIVE BACTERIA; PUC OPERON EXPRESSION; FNRL GENE; BRADYRHIZOBIUM-JAPONICUM; PHOTOSYSTEM FORMATION; TRANSDUCTION SYSTEM; OXYGEN REGULATION; COMPLEX-FORMATION;
Keywords:
cbb(3) cytochrome c oxidase; electron transport chain; gene regulation; photosynthesis; redox sensing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Kaplan, S Univ Texas, Hlth Sci Ctr, Dept Microbiol & Mol Genet, Sch Med, 6431 Fannin, Houston, TX 77030 USA Univ Texas 6431 Fannin Houston TX USA 77030 ouston, TX 77030 USA
Citazione:
J.I. Oh e S. Kaplan, "Redox signaling: globalization of gene expression", EMBO J, 19(16), 2000, pp. 4237-4247

Abstract

Here we show that the extent of electron flow through the cbb(3) oxidase of Rhodobacter sphaeroides :is inversely related to the expression levels ofthose photosynthesis genes that are under control of the PrrBA two-component activation system: the greater the electron flow, the stronger the inhibitory signal generated by the cbb(3) oxidase to repress photosynthesis geneexpression. Using site-directed mutagenesis, we show that intramolecular electron transfer within the cbb(3) oxidase is involved in signal generationand transduction and this signal does not directly involve the intervention of molecular oxygen. In addition to the cbb(3) oxidase, the redox state of the quinone pool controls the transcription rate of the puc operon via the AppA-PpsR antirepressor-repressor system. Together, these interacting regulatory circuits are depicted in a model that permits us to understand the regulation by oxygen and light of photosynthesis gene expression in R. sphaeroides.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:39:20