Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Effect of anti-infective ophthalmic solutions on corneal cells in vitro
Autore:
Matsumoto, S; Stern, ME;
Indirizzi:
Allergan Pharmaceut Inc, Irvine, CA 92615 USA Allergan Pharmaceut Inc Irvine CA USA 92615 eut Inc, Irvine, CA 92615 USA
Titolo Testata:
ADVANCES IN THERAPY
fascicolo: 3, volume: 17, anno: 2000,
pagine: 148 - 151
SICI:
0741-238X(200005/06)17:3<148:EOAOSO>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Keywords:
anti-infective; corneal cells; Ocuflox; Ciloxan; Tobramycin; cell membrane damage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Stern, ME Allergan Pharmaceut Inc, 2525 Dupont Dr, Irvine, CA 92615 USA Allergan Pharmaceut Inc 2525 Dupont Dr Irvine CA USA 92615 5 USA
Citazione:
S. Matsumoto e M.E. Stern, "Effect of anti-infective ophthalmic solutions on corneal cells in vitro", ADV THER, 17(3), 2000, pp. 148-151

Abstract

External ocular infections caused by susceptible strains of bacteria have recently been treated with potent broad-spectrum antimicrobial solutions. This study was conducted to compare the in vitro biologic effects of three anti-infective ophthalmic solutions (Ocuflox(R), Ciloxan(R), and Tobramycin(R)) on rabbit corneal epithelial cell cultures. Epithelial cell layers fromalbino rabbit eyes were isolated and incubated in culture media for 9 days, following which the cultures were rinsed and treated with the anti-infective solutions. Ciloxan and Tobramycin caused extensive ethidium bromide staining of the corneal epithelial cell layer after 5, 10, and 15 minutes, indicating acute cell membrane damage. Ocuflox ophthalmic solution caused lessethidium bromide staining at all evaluated times and, therefore, less cellmembrane damage than the comparator solutions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 08:29:34