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Titolo:
Exercise-induced bronchoconstriction depends on exercise load
Autore:
Carlsen, KH; Engh, G; Mork, M;
Indirizzi:
Voksentoppen Ctr Asthma & Allergy & Chron Lung Di, N-0791 Oslo, Norway Voksentoppen Ctr Asthma & Allergy & Chron Lung Di Oslo Norway N-0791 way Voksentoppen Res Inst Paediat Allergy Pulm & Mili, Oslo, Norway Voksentoppen Res Inst Paediat Allergy Pulm & Mili Oslo Norway o, Norway
Titolo Testata:
RESPIRATORY MEDICINE
fascicolo: 8, volume: 94, anno: 2000,
pagine: 750 - 755
SICI:
0954-6111(200008)94:8<750:EBDOEL>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDUCED ASTHMA; BRONCHIAL RESPONSIVENESS; CHILDREN; HYPERRESPONSIVENESS; STANDARDIZATION; BUDESONIDE; SEVERITY;
Keywords:
exercise-induced bronchoconstriction; exercise load; asthma; children; S-ECP; Borg score;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Carlsen, KH Voksentoppen Ctr Asthma & Allergy & Chron Lung Di, Ullveien 14, N-0791 Oslo, Norway Voksentoppen Ctr Asthma & Allergy & Chron Lung Di Ullveien 14 Oslo Norway N-0791
Citazione:
K.H. Carlsen et al., "Exercise-induced bronchoconstriction depends on exercise load", RESP MED, 94(8), 2000, pp. 750-755

Abstract

Exercise-induced bronchoconstriction (EIB) is often used as a measure of bronchial hyperresponsiveness and employed in epidemiological studies. Different tests are used, including free running tests with poor standardizationof exercise load. The present study aimed to assess the role of exercise load in relationship to level of EIB. Methods: 20 asthmatic children, 9-17 years old with a history of EIB, underwent two treadmill test with 85% and 95% exercise load. The children ran with increasing speed for the first 2 min until reaching a heart rare of 85%or 95% of calculated maximum (220 - age) and maintained this speed for thelast 4 min. Lung function was measured before running, and 0, 3, 6, 10 and15min after the run. Borg scale for perceived exertion was employed for children's self-evaluation of exercise load. Results: Peak heart rate, mean Borg score during 85% exercise load was 178.7/13.6 and during 95% was 194.3/18.2 (P<0.001). Maximum fall in FEV1 after85% exercise load was 8.84% vs. 25.11% after 95% (P<0.001). Nine subjects (40%) fell greater than or equal to 10% in FEV1 after 85% exercise load vs.20 subjects (1009/0) after 95% exercise load. EIB from the 95% exercise load test had markedly higher correlation with serum ECP (r=0.77, P<0.001). Conclusion: Exercise load is essential for the interpretation of EIB, and strict standardization of exercise tests should be undertaken. The EIB fromthe high exercise load tests seemed better correlated to inflammatory activity than the low exercise load test.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/02/20 alle ore 02:42:39