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Titolo:
Does intranasal application of zinc sulfate produce anosmia in the rat?
Autore:
Slotnick, B; Glover, P; Bodyak, N;
Indirizzi:
American Univ, Dept Psychol, Washington, DC 20016 USA American Univ Washington DC USA 20016 t Psychol, Washington, DC 20016 USA
Titolo Testata:
BEHAVIORAL NEUROSCIENCE
fascicolo: 4, volume: 114, anno: 2000,
pagine: 814 - 829
SICI:
0735-7044(200008)114:4<814:DIAOZS>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOUSE OLFACTORY EPITHELIUM; INDUCED PERIPHERAL ANOSMIA; MATERNAL-BEHAVIOR; ZNSO4 IRRIGATION; MALE-MICE; VOMERONASAL ORGAN; HOMING BEHAVIOR; GENE-EXPRESSION; LABORATORY RATS; SEXUAL-BEHAVIOR;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
131
Recensione:
Indirizzi per estratti:
Indirizzo: Slotnick, B American Univ, Dept Psychol, Washington, DC 20016 USA AmericanUniv Washington DC USA 20016 ashington, DC 20016 USA
Citazione:
B. Slotnick et al., "Does intranasal application of zinc sulfate produce anosmia in the rat?", BEHAV NEURO, 114(4), 2000, pp. 814-829

Abstract

Transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from olfactory sensory neurons to the olfactory bulb as well as odor detection and discrimination were examined in rats in which each nasal epithelium had been irrigated with 0.1-0.5 mi 5% zinc sulfate. After treatment, mts showed few or no deficits in discriminating among odors and in detecting high (1%-0.01%) concentrations of ethyl acetate, but some had deficits in detecting lower concentrations of the odor. In most cases, HRP reaction product filled more than 30% of olfactory bulb glomeruli 2-4 days after treatment with ZnSO4. The behavioral outcomes are in agreement with recent reports of considerable savings in olfaction even after severe reduction of afferent projections to the olfactory bulb. We conclude that, in the rat, intranasal application of ZnSO4, as generally practiced, does not produce anosmia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 11:41:41