Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Early release pattern of S100 protein as a marker of brain damage after warm cardiopulmonary bypass
Autore:
Ali, MS; Harmer, M; Vaughan, RS; Dunne, J; Latto, IP;
Indirizzi:
Univ Wales, Coll Med, Dept Anaesthet & Intens Care Med, Cardiff CF14 4XN, S Glam, Wales Univ Wales Cardiff S Glam Wales CF14 4XN Cardiff CF14 4XN, S Glam, Wales
Titolo Testata:
ANAESTHESIA
fascicolo: 8, volume: 55, anno: 2000,
pagine: 802 - 806
SICI:
0003-2409(200008)55:8<802:ERPOSP>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD CARDIOPLEGIA; CARDIAC OPERATIONS; COGNITIVE DYSFUNCTION; SURGERY; SERUM; S-100;
Keywords:
complications, neurological; surgery, cardiovascular; protein, S100;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Ali, MS Univ Wales, Coll Med, Dept Anaesthet & Intens Care Med, Heath Pk, Cardiff CF14 4XN, S Glam, Wales Univ Wales Heath Pk Cardiff S Glam Wales CF14 4XN N, S Glam, Wales
Citazione:
M.S. Ali et al., "Early release pattern of S100 protein as a marker of brain damage after warm cardiopulmonary bypass", ANAESTHESIA, 55(8), 2000, pp. 802-806

Abstract

Warm blood cardioplegia may be more beneficial to the heart than cold cardioplegia, but the effects of warm cardiopulmonary bypass and warm blood cardioplegia on the brain are controversial. S100 protein is an early marker of brain damage and has been detected alter cold cardiopulmonary bypass. We studied S100 concentrations in 20 patients undergoing coronary artery bypass surgery before and after warm cardiopulmonary bypass (34-37 degrees C) using warm blood cardioplegia (37 degrees C) for all patients. The peak levelof S100 protein occurred immediately after warm cardiopulmonary bypass, then decreased progressively until the last measurement at 4.5 h after bypass. The peak level appears to be dependent upon the age of the patient, with the following regression equation: y = -3.2 + 0.08x, where y is S100 protein concentration ill mu g.l(-1) and x is patient age in years. Further studies are needed to investigate the clinical significance of this early release pattern. Patient age should be taken into account when studying S100 protein levels after cardiopulmonary bypass.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 12:55:18