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Titolo:
Childhood vaccination against pneumococcal otitis media and pneumonia: An analysis of benefits and costs
Autore:
Weycker, D; Richardson, E; Oster, G;
Indirizzi:
Policy Anal Inc, Brookline, MA 02445 USA Policy Anal Inc Brookline MA USA02445 Anal Inc, Brookline, MA 02445 USA
Titolo Testata:
AMERICAN JOURNAL OF MANAGED CARE
fascicolo: 10, volume: 6, anno: 2000, supplemento:, S
pagine: S526 - S535
SICI:
1088-0224(200007)6:10<S526:CVAPOM>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
UNITED-STATES CHILDREN; ECONOMIC-ANALYSIS; RECOMMENDATIONS; IMMUNIZATION; PROGRAM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Oster, G Policy Anal Inc, 4 Davis Court, Brookline, MA 02445 USA Policy Anal Inc 4 Davis Court Brookline MA USA 02445 MA 02445 USA
Citazione:
D. Weycker et al., "Childhood vaccination against pneumococcal otitis media and pneumonia: An analysis of benefits and costs", AM J M CARE, 6(10), 2000, pp. S526-S535

Abstract

Objective: To examine the economic benefits and costs of routine vaccination of children younger than 5 years of age against pneumococcal otitis media and pneumonia with the pneumococcal conjugate vaccine. Study Design: A decision-analytic model of the cumulative numbers of casesand costs to age 10 years of acute otitis media (AOM), tympanostomy and related procedures (TRP), and community-acquired pneumonia (CAP) in children who either did or did not receive the pneumococcal conjugate vaccine. Patients and Methods: Seven hypothetical cohorts of 1000 children, stratified by age at initial vaccination, were followed. Outcome measures include costs of vaccination, cumulative numbers of cases of AOM, TRP, and CAP to age 10 years, and related disease costs, including medical treatment and parental work loss. Results: Routine vaccination of 1000 children against pneumococcal infection would cost between $57,000 and $226,000, depending on age (the recommended number of doses varies by age at initial vaccination). Acute otitis media, TRP, and CAP to age 10 years would decline by 139 to 330, 8 to 22, and 15 to 30 cases, respectively; costs of medical treatment and work loss wouldcorrespondingly decline by $56,000 to $138,000. Expected net economic benefits (benefits minus costs) of vaccination against pneumococcal otitis media and pneumonia range from -$88,000 to $15,000 for children less than 2 years of age, and from -$1,000 to $31,000 for those aged 2 to 5 years at vaccination. Conclusion: Routine vaccination against pneumococcal otitis media and pneumonia appears to be cost-increasing for children less than 2 years of age who require multiple doses, but cost-saving for children aged 2 to 5 years who would require only a single dose of the vaccine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:41:09