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Titolo:
Use of 'locked-in' antibiotic to treat an unusual gram-negative hemodialysis catheter infection
Autore:
Shah, J; Feinfeld, DA;
Indirizzi:
Nassau Cty Med Ctr, Dept Med, E Meadow, NY 11554 USA Nassau Cty Med Ctr EMeadow NY USA 11554 Dept Med, E Meadow, NY 11554 USA SUNY Hlth Sci Ctr, Stony Brook, NY USA SUNY Hlth Sci Ctr Stony Brook NY USA Y Hlth Sci Ctr, Stony Brook, NY USA
Titolo Testata:
NEPHRON
fascicolo: 4, volume: 85, anno: 2000,
pagine: 348 - 350
SICI:
0028-2766(200008)85:4<348:UO'ATT>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL VENOUS CATHETERS; PREVENTION; COLONIZATION; BACTEREMIA; TRIAL;
Keywords:
hemodialysis; tunneled catheter, infection; Xanthomonas maltophilia; locked-in antibiotic;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Feinfeld, DA Nassau Cty Med Ctr, Dept Med, 2201 Hempstead Turnpike, E Meadow, NY 11554 USA Nassau Cty Med Ctr 2201 Hempstead Turnpike E Meadow NY USA11554
Citazione:
J. Shah e D.A. Feinfeld, "Use of 'locked-in' antibiotic to treat an unusual gram-negative hemodialysis catheter infection", NEPHRON, 85(4), 2000, pp. 348-350

Abstract

A 37-year-old woman on maintenance hemodialysis for 3 years had multiple vascular access failures due to antiphospholipid syndrome, She was dialyzed via a tunneled left subclavian catheter, but after 1 year developed chills and fever during each dialysis session. Blood cultures grew out Xanthomonasmaltophilia sensitive to ceftazidime and ciprofloxacin, Intravenous administration of both antibiotics failed to eradicate infection, We added 'locked-in' ceftazidime, instilling it daily into the catheter along with heparinized saline for 3 weeks. Within 24 h the patient was dialyzed uneventfully,and all subsequent blood cultures have been negative. This case shows the successful use of a 'locked-in' antibiotic to treat an unusual gram-negative catheter infection. Two prior series have reported similar good results in infections with more common organisms. Such treatment may permit continued use of tunneled hemodialysis catheters for longer periods. Copyright (C) 2000 S. Karger AG, Basel.

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Documento generato il 11/07/20 alle ore 20:39:45