Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Failure of thrombolysis: experience with a policy of early angiography andrescue angioplasty for electrocardiographic evidence of failed thrombolysis
Autore:
Sutton, AGC; Campbell, PG; Grech, ED; Price, DJA; Davies, A; Hall, JA; Stewart, MJ; de Belder, MA;
Indirizzi:
S Cleveland Hosp, Cardiothorac Div, Middlesbrough TS4 3BW, Cleveland, England S Cleveland Hosp Middlesbrough Cleveland England TS4 3BW eveland, England
Titolo Testata:
HEART
fascicolo: 2, volume: 84, anno: 2000,
pagine: 197 - 204
SICI:
1355-6037(200008)84:2<197:FOTEWA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; AORTIC COUNTERPULSATION; CORONARY ANGIOPLASTY; RANDOMIZED TRIAL; CARDIOGENIC-SHOCK; MORTALITY; ARTERY; OUTCOMES; PATENCY; THERAPY;
Keywords:
acute myocardial infarction; rescue angioplasty; failed reperfusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: de Belder, MA S Cleveland Hosp, Cardiothorac Div, Marton Rd, MiddlesbroughTS4 3BW, Cleveland, England S Cleveland Hosp Marton Rd Middlesbrough Cleveland England TS4 3BW
Citazione:
A.G.C. Sutton et al., "Failure of thrombolysis: experience with a policy of early angiography andrescue angioplasty for electrocardiographic evidence of failed thrombolysis", HEART, 84(2), 2000, pp. 197-204

Abstract

Objective-To assess the outcome of a policy of emergency coronary angiography with or without rescue angioplasty in patients with acute myocardial infarction and ECG evidence of failed reperfusion after thrombolysis. Design-A cohort studySetting-Regional cardiothoracic unit. Patients-197 patients with acute myocardial infarction fulfilling a simpleECG criterion of failed reperfusion. Interventions-Emergency coronary angiography proceeding to rescue angioplasty for inadequate antegrade flow. Main outcome measures-Hospital mortality for all 197 patients; incidence of successful and failed rescue angioplasty; need for additional revascularisation in those receiving rescue angioplasty compared with those not treated in this way. Results-197 patients had emergency angiography for ECG evidence of failed reperfusion; 156 patients received immediate rescue angioplasty. Overall hospital mortality for those undergoing rescue angioplasty was 11.5%. Rescue angioplasty achieved TIMI 2 (11) or TIMI 3 (124) in 135 patients, who had ahospital mortality of 5.9%. Failure to achieve at least TIMI 2 flow following rescue angioplasty occurred in 21 patients, with a hospital mortality of 48%. In the 41 patients in whom immediate rescue angioplasty was not performed, reinfarction or requirement for revascularisation occurred in 37%. Reinfarction occurred in three patients (1.9%) who had immediate rescue angioplasty. Hospital mortality for the whole cohort was 10.7%. Conclusions-A policy of emergency coronary angiography proceeding to rescue angioplasty where appropriate reduces mortality in a high risk group to alevel less than expected for patients with acute myocardial infarction andECG evidence of failed reperfusion. Unsuccessful rescue angioplasty is associated with a high mortality.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:59:29