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Titolo:
Associations between cerebral blood-flow measured by single photon emission computed tomography (SPECT), electro-encephalogram (EEG), behaviour symptoms, cognition and neurological soft signs in children with attention-deficit hyperactivity disorder (ADHD)
Autore:
Gustafsson, P; Thernlund, G; Ryding, E; Rosen, I; Cederblad, M;
Indirizzi:
Malmo Univ Hosp, Dept Child & Adolescent Psychiat, SE-2 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-2 dolescent Psychiat, SE-2 Malmo, Sweden Univ Lund Hosp, Dept Child & Adolescent Psychiat, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 escent Psychiat, S-22185 Lund, Sweden Univ Lund Hosp, Dept Clin Neurophysiol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 in Neurophysiol, S-22185 Lund, Sweden
Titolo Testata:
ACTA PAEDIATRICA
fascicolo: 7, volume: 89, anno: 2000,
pagine: 830 - 835
SICI:
0803-5253(200007)89:7<830:ABCBMB>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
DYSFUNCTION; ADVERSITY;
Keywords:
ADHD; child behaviour problem; soft neurological signs; SPECT; WISC;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Gustafsson, P Malmo Univ Hosp, Dept Child & Adolescent Psychiat, SE-2 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-2 hiat, SE-2 Malmo, Sweden
Citazione:
P. Gustafsson et al., "Associations between cerebral blood-flow measured by single photon emission computed tomography (SPECT), electro-encephalogram (EEG), behaviour symptoms, cognition and neurological soft signs in children with attention-deficit hyperactivity disorder (ADHD)", ACT PAEDIAT, 89(7), 2000, pp. 830-835

Abstract

Twenty-eight children with attention-deficit hyperactivity disorder (ADHD)were examined with SPECT (single photon emission computed tomography). Seven of the children had abnormal distribution of the regional cerebral blood-flow (rCBF) on visual evaluation and 10 had abnormal EEG findings. The only clinical finding that differentiated the group with normal from abnormal rCBF was behaviour symptom load. A factor analysis of the rCBF in differentregions of interest yielded one factor with low rCBF in the temporal and cerebellar regions and high rCBF in the subcortical and thalamic regions, which was significantly associated with the degree of motor impairment and results on a cognitive test (WISC). Another factor consisting of high rCBF infrontal and parietal regions had a significant negative correlation with the degree of behaviour symptoms. There was a negative correlation between the rCBF in the right frontal regions and the degree of behaviour symptoms. The number of minor physical anomalies (MPA) was negatively correlated to the rCBF in the frontal lobes bilaterally. These results suggest that there may be at least two functional disturbances in ADHD, one specific neurodevelopmentally determined disturbance of thefrontal lobes, especially of the right hemisphere, related to behaviour deviance, and another disturbance of the integration of the temporal lobes, the cerebellum and subcortical structures, related to motor planning and aspects of cognition.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 02:15:37