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Titolo:
Breast lesions: Evaluation with dynamic contrast-enhanced T1-weighted MR imaging and with T2*-weighted first-pass perfusion MR imaging
Autore:
Kvistad, KA; Rydland, J; Vainio, J; Smethurst, HB; Lundgren, S; Fjosne, HE; Haraldseth, O;
Indirizzi:
Univ Trondheim Hosp, MR Ctr, Div Med, N-7006 Trondheim, Norway Univ Trondheim Hosp Trondheim Norway N-7006 ed, N-7006 Trondheim, Norway Univ Trondheim Hosp, Dept Pathol, N-7006 Trondheim, Norway Univ Trondheim Hosp Trondheim Norway N-7006 ol, N-7006 Trondheim, Norway Univ Trondheim Hosp, Dept Oncol, N-7006 Trondheim, Norway Univ Trondheim Hosp Trondheim Norway N-7006 ol, N-7006 Trondheim, Norway Univ Trondheim Hosp, Dept Surg, N-7006 Trondheim, Norway Univ Trondheim Hosp Trondheim Norway N-7006 rg, N-7006 Trondheim, Norway
Titolo Testata:
RADIOLOGY
fascicolo: 2, volume: 216, anno: 2000,
pagine: 545 - 553
SICI:
0033-8419(200008)216:2<545:BLEWDC>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATHOLOGICAL CORRELATION; SUSCEPTIBILITY-CONTRAST; MAMMOGRAPHY; TUMORS; DIAGNOSIS; CANCER; RESOLUTION; CARCINOMA; FEATURES; BIOPSY;
Keywords:
breast neoplasms, diagnosis; breast neoplasms, MR; magnetic resonance (MR); magnetic resonance (MR), perfusion study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Kvistad, KA Univ Trondheim Hosp, MR Ctr, Div Med, N-7006 Trondheim, NorwayUniv Trondheim Hosp Trondheim Norway N-7006 rondheim, Norway
Citazione:
K.A. Kvistad et al., "Breast lesions: Evaluation with dynamic contrast-enhanced T1-weighted MR imaging and with T2*-weighted first-pass perfusion MR imaging", RADIOLOGY, 216(2), 2000, pp. 545-553

Abstract

PURPOSE: To evaluate the diagnostic value of an imaging protocol that combines dynamic contrast-enhanced T1-weighted magnetic resonance (MR) imaging and T2*-weighted first-pass perfusion imaging in patients with breast tumors and to determine if T2*-weighted imaging can provide additional diagnostic information to that obtained with T1-weighted imaging. MATERIALS AND METHODS: One hundred thirty patients with breast tumors underwent MR imaging with dynamic contrast-enhanced T1-weighted imaging of the entire breast, which was followed immediately with single-section, imaging of the tumor. RESULTS: With T2*-weighted perfusion imaging, 57 of 72 carcinomas but onlyfour of 58 benign lesions had a signal intensity loss of 20% or more during the first pass, for a sensitivity of 79% and a specificity of 93%. With dynamic contrast-enhanced T1-weighted imaging, 64 carcinomas and 19 benign lesions showed a signal intensity increase of 90% or more in the first imageobtained after the administration of contrast material, for a sensitivity of 89% and a specificity of 67%. CONCLUSION: T2*-weighted first-pass perfusion imaging can help differentiate between benign and malignant breast lesions with a high level of specificity. The combination of T1-weighted and T2*-weighted imaging is feasible in a single patient examination and may improve breast MR imaging.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 04:45:51