Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Some proposals regarding the organization of the central nervous system control of penile erection
Autore:
McKenna, KE;
Indirizzi:
Northwestern Univ, Sch Med, Dept Physiol, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 ept Physiol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Urol M211, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 t Urol M211, Chicago, IL 60611 USA
Titolo Testata:
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
fascicolo: 5, volume: 24, anno: 2000,
pagine: 535 - 540
SICI:
0149-7634(200007)24:5<535:SPRTOO>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDUCED FOS IMMUNOREACTIVITY; MEDIAL PREOPTIC NUCLEUS; SPINAL SEXUAL REFLEXES; MALE-RATS; TRANSNEURONAL TRANSPORT; PARAVENTRICULAR NUCLEUS; ANDROGEN RECEPTORS; PSEUDORABIES VIRUS; PUDENDAL MOTOR; FEMALE RATS;
Keywords:
penis; erectile dysfunction; impotence; sexual responses;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: McKenna, KE Northwestern Univ, Sch Med, Dept Physiol, 303 E Chicago Ave, Chicago, IL 60611 USA Northwestern Univ 303 E Chicago Ave Chicago IL USA 60611 1 USA
Citazione:
K.E. McKenna, "Some proposals regarding the organization of the central nervous system control of penile erection", NEUROSCI B, 24(5), 2000, pp. 535-540

Abstract

Recent research on the central nervous control of penile erection is discussed. A framework for this control is based upon principles put forward by Frank Beach regarding the neuroendocrine regulation of male copulatory behavior. The current discussion is focused primarily on a subset, penile erection, The spinal cord contains all the necessary components for the production of penile erection. This requires a multisegmental coordination among penile vasodilator and vasoconstrictor autonomic neurons, pudendal motoneurons responsible for penile rigidity and autonomic neurons which control extra-penile blood flow. Genital sensory stimulation can activate this spinal network. The spinal cord is also under excitatory and inhibitory control fromsupraspinal sites. Penile erection can be driven by supraspinal input alone and supraspinal control can inhibit the erectile effects of genital stimulation. An important aspect of the CNS control of penile erection is that there are extensive interconnections between most of the brain sites identified to date, Most of the pathways are characterized by reciprocal connections, A large number of the CNS sites also receive genital sensory information. Thus, descending control may itself be modulated by ascending sensory pathways which relay information from the genitalia. This raises the possibility that penile erection may involve a positive feedback system. Receptors for gonadal hormones have been identified throughout the neuraxis. However, strongevidence for the control of male sexual function by gonadal hormones has been identified only for forebrain sites. The functional role of brainstem and spinal gonadal hormone receptors has not yet been clarified. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 20:41:07