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Titolo:
ELEVATED LEVELS OF INTERLEUKIN-6 IN THE FOLLICULAR-FLUID AT THE TIME OF OOCYTE RETRIEVAL FOR IN-VITRO FERTILIZATION MAY PREDICT THE DEVELOPMENT OF EARLY-FORM OVARIAN HYPERSTIMULATION SYNDROME
Autore:
GEVA E; LESSING JB; LERNERGEVA L; AZEM F; YOVEL I; AMIT A;
Indirizzi:
SERLIN MATERN HOSP,IVF UNIT,TEL AVIV SOURASKY MED CTR,POB 7079 IL-61070 TEL AVIV ISRAEL SERLIN MATERN HOSP,IVF UNIT,TEL AVIV SOURASKY MED CTR IL-61070 TEL AVIV ISRAEL CHAIM SHEBA MED CTR,DEPT CLIN EPIDEMIOL TEL AVIV ISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Fertility and sterility
fascicolo: 1, volume: 68, anno: 1997,
pagine: 133 - 137
SICI:
0015-0282(1997)68:1<133:ELOIIT>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-NECROSIS-FACTOR; FACTOR-ALPHA; INVITRO FERTILIZATION; TESTOSTERONE LEVELS; RISK-FACTORS; PROGESTERONE; CELLS; ANGIOGENESIS; FOLLICLES; ESTRADIOL;
Keywords:
IL-2; IL-6; IVF; OHSS; TNF-ALPHA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
E. Geva et al., "ELEVATED LEVELS OF INTERLEUKIN-6 IN THE FOLLICULAR-FLUID AT THE TIME OF OOCYTE RETRIEVAL FOR IN-VITRO FERTILIZATION MAY PREDICT THE DEVELOPMENT OF EARLY-FORM OVARIAN HYPERSTIMULATION SYNDROME", Fertility and sterility, 68(1), 1997, pp. 133-137

Abstract

Objective: To determine the possible predictive role of interleukin-2(IL-2), IL-6, and tumor necrosis factor (TNF-alpha) in the development of early-form ovarian hyperstimulation syndrome (OHSS). Design: Nested, case-control study. Setting: An IVF unit, university-based program. Patient(s): Follicular fluid (FF) was obtained from 322 high responders. The study group and control group comprised 10 patients who developed early, severe OHSS and 10 who did not develop OHSS, respectively. An additional control group included 10 low-responder patients who did not develop OHSS. Intervention(s): Ovulation induction with hMG combined with GnRH analogue. Main Outcome Measure(s): All FF samples were tested for IL-2, IL-6, and TNF-alpha. The patient's serum was tested for mean E-2 and P concentrations. Result(s): Interleukin-g levels in the FF were significantly higher in the OHSS group than in the two control groups, whereas no differences were found in IL-2 and TNF-alpha. No correlation was found between the FF concentrations of IL-2, IL-6, and TNF-alpha and the mean serum E-2 levels or the number of oocytes retrieved. Conclusion(s): Elevated levels of IL-6 in the preovulatory FFat the time of oocyte retrieval for IVF may predict the development of early-form OHSS in high responders. (C) 1997 by American Society forReproductive Medicine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 02:23:22