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Titolo:
Changes of the T-wave amplitude and angle: An early marker of altered ventricular repolarization in hypertension
Autore:
Dilaveris, P; Gialafos, E; Poloniecki, J; Hnatkova, K; Richter, D; Andrikopoulos, G; Lazaki, E; Gialafos, J; Malik, M;
Indirizzi:
St George Hosp, Sch Med, Dept Cardiol Sci, London SW17 0RE, England St George Hosp London England SW17 0RE iol Sci, London SW17 0RE, England Hippokration Hosp, State Dept Cardiol, Athens, Greece Hippokration Hosp Athens Greece osp, State Dept Cardiol, Athens, Greece
Titolo Testata:
CLINICAL CARDIOLOGY
fascicolo: 8, volume: 23, anno: 2000,
pagine: 600 - 606
SICI:
0160-9289(200008)23:8<600:COTTAA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
QT INTERVAL DISPERSION; ELECTROCARDIOGRAPHIC LEADS; PROGNOSTIC IMPLICATIONS; MYOCARDIAL-INFARCTION; HYPERTROPHY; REPRODUCIBILITY; ABNORMALITIES; ARRHYTHMIAS; METHODOLOGY; MORTALITY;
Keywords:
T loop; maximum vector; QT dispersion; ventricular repolarization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Malik, M St George Hosp, Sch Med, Dept Cardiol Sci, London SW17 0RE, England St George Hosp London England SW17 0RE London SW17 0RE, England
Citazione:
P. Dilaveris et al., "Changes of the T-wave amplitude and angle: An early marker of altered ventricular repolarization in hypertension", CLIN CARD, 23(8), 2000, pp. 600-606

Abstract

Background: The heterogeneity of ventricular repolarization is an important proarrhythmic factor. QT dispersion has been proposed to reflect the inhomogeneity of ventricular repolarization, but a poor reproducibility limits its clinical applicability. Reliable noninvasive methods to quantify abnormalities in ventricular repolarization are still lacking. The T-loop morphology analysis is a novel method aimed at quantifying ventricular repolarization. Hypothesis: To test the ability of the T-loop morphology analysis to discriminate between hypertensive patients and healthy subjects, 105 hypertensive patients (mean age 63.6 +/- 12.3 years) and 110 healthy controls (mean age 49.7 +/- 14.3 years) were evaluated. Methods: The maximum QT interval (QT maximum), the minimum QT interval (QTminimum), and their difference (QT dispersion) were calculated from a digitally recorded 12-lead electrocardiogram (ECG) in both study groups. X, Y, and Z leads were reconstructed from the 12-lead EGG, and the amplitude of the maximum T vector (T amplitude) and the angle between the maximum T vector and X axis (T angle) were calculated from the projection of the T loop inthe frontal plane. Results: T amplitude (p<0.001), T angle (p = 0.05), and QT dispersion (p =0.04) were significantly different between hypertensive patients and controls, while QT maximum (p = 0.14) and QT minimum (p = 0.35) did not differ between the groups. T amplitude was the only marker which differed between hypertensive patients without ECG criteria for left ventricular hypertrophy and controls (p = 0.002). Conclusions: T-loop features and particularly T amplitude are significantly different between hypertensive patients and healthy controls and may serve as early markers of repolarization abnormalities in a hypertensive population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 08:25:04