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Titolo:
Serum anti-s100b, anti-GFAP and anti-NGF autoantibodies of IgG class in healthy persons and patients with mental and neurological disorders
Autore:
Poletaev, AB; Morozov, SG; Gnedenko, BB; Zlunikin, VM; Korzhenevskey, DA;
Indirizzi:
Med & Ecol Fund Chernobyl Test, Moscow, Russia Med & Ecol Fund Chernobyl Test Moscow Russia nobyl Test, Moscow, Russia
Titolo Testata:
AUTOIMMUNITY
fascicolo: 1, volume: 32, anno: 2000,
pagine: 33 - 38
SICI:
0891-6934(2000)32:1<33:SAAAAA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
NATURAL AUTOANTIBODIES; ANTIBODIES; BRAIN; NERVE;
Keywords:
natural autoantibodies; brain proteins; mental and neurological disorders;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Poletaev, AB 102-47 Profsoyuznaja St,Apt 143, Moscow 117485, Russia 102-47 Profsoyuznaja St,Apt 143 Moscow Russia 117485 Russia
Citazione:
A.B. Poletaev et al., "Serum anti-s100b, anti-GFAP and anti-NGF autoantibodies of IgG class in healthy persons and patients with mental and neurological disorders", AUTOIMMUN, 32(1), 2000, pp. 33-38

Abstract

Natural autoantibodies of Ige class to proteins S100b, glial fibrillar acidic protein (GFAP), and nerve growth factor (NGF) are presented in serum ofhealthy adults and those levels/affinities are relatively constant and mayvary among individuals within narrow limits, In patients with depressive disorder, epilepsy, multiple sclerosis, and Parkinson's disease dispersion of such autoantibodies serum levels were often found beyond the normal ranges. Most of the patient groups include cases with significantly elevated as well as abnormally decreased immunoreactivity parameters. This leads us to assumption that changes in some basic mechanisms of individual immune staterepresent the common features of different forms of pathology of the nervous system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 13:20:13