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Titolo:
A CASE-CONTROL STUDY ON ALCOHOL AND SEIZURES - STUDY DESIGN, PROTOCOL, AND DATA-COLLECTION
Autore:
LEONE M; BOTTACCHI E; BEGHI E; MORGANDO E; MUTANI R; AMEDEO G; CREMO R; GIANELLI M; RAVAGLI CL; SIRONI L; BRIGNOLIO F; DUC E; MONTANO V; TRIBOLO A; NARDOZZA V; GIONCO M; GRASSO E; MEINERI P; ROSSO MG; VILLANI A; MARGAROLI A; JULITA P; SAVOINI G; CAVALLI A; DEANGELIS MS; NALDI P; TERAZZI E; TINEBRA M; CAMPANELLA A; DEMATTEI M; ROCCI E; ZAINA P; NOBILI M; VIVALDA L; LEOTTA D; MORINO U; BACCI R; DANIELE D; RUBINO R; PROVERA P; ANDREOTTI M; MITTINO D;
Indirizzi:
UNIV NOVARA,OSPED MAGGIORE,DIV NEUROL,CSO MAZZINI 18 I-28100 NOVARA ITALY UNIV TURIN,FAC MED & CHIRURG NOVARA,DIV NEUROL TURIN ITALY OSPED REG,UO NEUROL & NEUROFISIOPATOL AOSTA ITALY IST RIC FARMACOL MARIO NEGRI,LAB FARMACOL CLIN MILAN ITALY UNIV MILAN,OSPED S GERARDO,NEUROL CLIN MONZA ITALY OSPED MOLINETTE,DEA NEUROL TURIN ITALY
Titolo Testata:
Italian journal of neurological sciences
fascicolo: 2, volume: 18, anno: 1997,
pagine: 119 - 124
SICI:
0392-0461(1997)18:2<119:ACSOAA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSUMPTION; RISK;
Keywords:
EPILEPSY; ALCOHOL DRINKING; ALCOHOLISM; QUESTIONNAIRE; OBSERVER-VARIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
M. Leone et al., "A CASE-CONTROL STUDY ON ALCOHOL AND SEIZURES - STUDY DESIGN, PROTOCOL, AND DATA-COLLECTION", Italian journal of neurological sciences, 18(2), 1997, pp. 119-124

Abstract

We designed a multicenter case control study to evaluate whether chronic alcoholism and alcohol consumption ape risk factors for developinga first generalized tonic-clonic epileptic seizure. Cases were 278 patients (92 women, 186 men), with a first generalized tonic-clonic seizure (either idiopathic or symptomatic), matched to 556 controls for center, sex, age, and weekday of the seizure. Information on risk factors was obtained through a questionnaire. This paper focuses on the study design (selection of cases and choice of controls), the validity of the instruments for data collection and the strategies of study conduction (interviews, use of proxy respondents). Inter-rater agreement wasexcellent for drinking status, patterns of drinking, and broad indicators of consumption (yes/no). Agreement was variable for the number ofservings/week, but was excellent (r=0.91) for a summary measure of daily alcohol intake.

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Documento generato il 29/11/20 alle ore 06:47:48