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Titolo:
Motor response suppression and the prepotent tendency to respond: a parametric fMRI study
Autore:
de Zubicaray, GI; Andrew, C; Zelaya, FO; Williams, SCR; Dumanoir, C;
Indirizzi:
Inst Psychiat, London, England Inst Psychiat London EnglandInst Psychiat, London, England Univ Technol Compiegne, F-60206 Compiegne, France Univ Technol Compiegne Compiegne France F-60206 -60206 Compiegne, France
Titolo Testata:
NEUROPSYCHOLOGIA
fascicolo: 9, volume: 38, anno: 2000,
pagine: 1280 - 1291
SICI:
0028-3932(2000)38:9<1280:MRSATP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREFRONTAL CORTEX INVOLVEMENT; SUSTAINED ATTENTION DEFICITS; FUNCTIONAL MRI; FRONTAL-LOBE; HUMAN BRAIN; PARIETAL CORTEX; PREMOTOR CORTEX; WORKING-MEMORY; LESIONS; DISCRIMINATION;
Keywords:
functional MRI; motor response suppression; prefrontal cortex; inhibition of prepotent responses;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Citazione:
G.I. de Zubicaray et al., "Motor response suppression and the prepotent tendency to respond: a parametric fMRI study", NEUROPSYCHO, 38(9), 2000, pp. 1280-1291

Abstract

In the present study we utilised functional magnetic resonance imaging (fMRI) to examine cerebral activation during performance of a classic motor task in which response suppression load was parametrically varied. Linear increases in activity were observed in a distributed network of regions acrossboth cerebral hemispheres, although with more extensive involvement of theright prefrontal cortex. Activated regions included prefrontal, parietal and occipitotemporal cortices. Decreasing activation was similarly observed in a distributed network of regions, These response forms are discussed in terms of an increasing requirement for visual cue discrimination and suppression/selection of motor responses, and a decreasing probability of the occurrence of non-target stimuli and attenuation of a prepotent tendency to respond. The results support recent proposals for a dominant role for the right-hemisphere in performance of motor response suppression tasks that emphasise the importance of the right prefrontal cortex. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 03:04:17