Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Morphological alteration of temporal lobe gray matter in dyslexia: An MRI study
Autore:
Eliez, S; Rumsey, JM; Giedd, JN; Schmitt, JE; Patwardhan, AJ; Reiss, AL;
Indirizzi:
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 t & Behav Sci, Stanford, CA 94305 USA NIMH, Rockville, MD 20857 USA NIMH Rockville MD USA 20857NIMH, Rockville, MD 20857 USA NIMH, Bethesda, MD 20892 USA NIMH Bethesda MD USA 20892NIMH, Bethesda, MD 20892 USA Stanford Univ, Sch Med, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 Univ, Sch Med, Stanford, CA 94305 USA
Titolo Testata:
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
fascicolo: 5, volume: 41, anno: 2000,
pagine: 637 - 644
SICI:
0021-9630(200007)41:5<637:MAOTLG>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; DEVELOPMENTAL DYSLEXIA; PLANUM TEMPORALE; BRAIN; HANDEDNESS; ASYMMETRY; CHILDREN; CORTEX; PARCELLATION; ACTIVATION;
Keywords:
brain development; brain imaging; cerebral lateralization; dyslexia; reading; temporal lobe;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Eliez, S Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, 401 Quarry Rd,Stanford, CA 94305 USA Stanford Univ 401 Quarry Rd Stanford CA USA 94305 d, CA 94305 USA
Citazione:
S. Eliez et al., "Morphological alteration of temporal lobe gray matter in dyslexia: An MRI study", J CHILD PSY, 41(5), 2000, pp. 637-644

Abstract

Functional imaging studies of developmental dyslexia have reported reducedtask-related neural activity in the temporal and inferior parietal cortices. To examine the possible contribution of subtle anatomic deviations to these reductions, volumes were measured for the major lobes of the brain, thesubcortical nuclei, cerebellum, and lateral ventricles on magnetic resonance imaging (MRI) scans from 16 right-handed dyslexic men, ages 18 to 40, and 14 matched controls, most of whom had previously undergone PET imaging. Aspecific decrease in tissue volume was localized to the temporal lobes andwas particularly prominent on the left (p < .01). An analysis of tissue composition revealed that this reduction was primarily attributable to decreased gray matter within the left temporal lobe (p < .002). Further segmentation of the temporal lobe showed that this reduction was not confined to thesuperior temporal gyrus, the primary location of primary auditory cortex. Reductions of temporal lobe gray matter may reflect a regional decrease in neuronal number or neuropil, which in turn may result in reading impairment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:36:00