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Titolo:
Clinical cross-reactivity among foods of the Rosaceae family
Autore:
Rodriguez, J; Crespo, JF; Lopez-Rubio, A; de la Cruz-Bertolo, J; Ferrando-Vivas, P; Vives, R; Daroca, P;
Indirizzi:
Univ Madrid, Hosp Doce Octubre, Serv Alergia, E-28041 Madrid, Spain Univ Madrid Madrid Spain E-28041 re, Serv Alergia, E-28041 Madrid, Spain Univ Madrid, Hosp Doce Octubre, Unidad Invest, E-28041 Madrid, Spain Univ Madrid Madrid Spain E-28041 e, Unidad Invest, E-28041 Madrid, Spain
Titolo Testata:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
fascicolo: 1, volume: 106, anno: 2000,
parte:, 1
pagine: 183 - 189
SICI:
0091-6749(200007)106:1<183:CCAFOT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIPID TRANSFER PROTEIN; ORAL ALLERGY SYNDROME; MAJOR ALLERGEN; POLLEN ALLERGY; DOUBLE-BLIND; PEACH; APPLE; HYPERSENSITIVITY; CHILDREN; CHERRY;
Keywords:
food hypersensitivity; fruit; Rosaceae; double-blind placebo-controlled food challenge; skin prick lest; CAP system FEIA; clinical cross-reactivity; apple; peach; apricot;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Rodriguez, J Univ Madrid, Hosp Doce Octubre, Serv Alergia, Ctra Andalucia,Km 5-400, E-28041 Madrid, Spain Univ Madrid Ctra Andalucia,Km 5-400 MadridSpain E-28041 ain
Citazione:
J. Rodriguez et al., "Clinical cross-reactivity among foods of the Rosaceae family", J ALLERG CL, 106(1), 2000, pp. 183-189

Abstract

been increasingly reported as causes of allergic reaction. Patients frequently have positive skin tests or radioallergosorbent test results for multiple members of this botanical family. Objective: Our purpose was to investigate the clinical crossreactivity assessed by double-blind, placebo-controlled food challenge (DBPCFC) of Rosaceae foods (apricot, almond, plum, strawberry, apple, peach, and pear). Methods: Thirty-four consecutive adult patients complaining of adverse reactions to Rosaceae were included in the study. Skin prick tests and CAP System (FEIA) were performed with Rosaceae foods in all patients. Clinical reactivity to Rosaceae was systematically evaluated by open food challenges (OFCs), unless there was a convincing history of a recent severe anaphylaxis,Positive reactions an OFCs were subsequently evaluated by DBPCFCs,Results: Twenty-six and 24 patients had positive skin prick tests and CAP FEIA with Rosaceae, respectively; from these 88% and 100% had positive tests with greater than or equal to 2. No evidence of clinical reactivity was found in 66% percent of positive skin prick tests and 63% of positive specific IgE determinations to fruits. A total of 226 food challenges (including OFC and DBPCFC) were performed in the 28 patients with positive skin prick tests or CAP System FEIA. Of 182 initial OFCs carried out, 26 (14%) reactions were confirmed by DBPCFCs, Overall, 40 reactions were considered positive in 22 patients with positive skin tests or CAP FEIA, Thirty-eight reactions had been previously reported, the remaining two were detected by systematic challenges. Most reactions were caused by peach (22 patients), apple (6), and apricot (5), Ten patients (46%) were clinically allergic to peach and other Rosaceae,Conclusion: Positive skin test and CAP System FEIA should not be taken as the only guide for multi-species dietary restrictions. Nevertheless, the potential clinical allergy to other Rosaceae should not be neglected. If the reported reaction is confirmed, current tolerance to other Rosaceae should be precisely established unless there has been ingestion without symptoms after the reaction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/21 alle ore 04:27:40