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Titolo:
Hypertension risk status and effect of caffeine on blood pressure
Autore:
Hartley, TR; Sung, BH; Pincomb, GA; Whitsett, TL; Wilson, MF; Lovallo, WR;
Indirizzi:
Vet Affairs Med Ctr, Oklahoma City, OK 73104 USA Vet Affairs Med Ctr Oklahoma City OK USA 73104 klahoma City, OK 73104 USA Univ Oklahoma, Hlth Sci Ctr, Dept Psychiat & Behav Sci, Oklahoma City, OK 73190 USA Univ Oklahoma Oklahoma City OK USA 73190 Sci, Oklahoma City, OK 73190 USA Univ Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK USA Univ Oklahoma Oklahoma City OK USA Ctr, Dept Med, Oklahoma City, OK USA Millard Fillmore Hlth Care Syst, Buffalo, NY USA Millard Fillmore Hlth Care Syst Buffalo NY USA are Syst, Buffalo, NY USA SUNY Buffalo, Buffalo, NY 14260 USA SUNY Buffalo Buffalo NY USA 14260SUNY Buffalo, Buffalo, NY 14260 USA
Titolo Testata:
HYPERTENSION
fascicolo: 1, volume: 36, anno: 2000,
pagine: 137 - 141
SICI:
0194-911X(200007)36:1<137:HRSAEO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
YOUNG MEN; COFFEE; EXERCISE; STRESS;
Keywords:
caffeine; diet; hypertension, detection and control; blood pressure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Lovallo, WR Vet Affairs Med Ctr, 151A,921 NE 13th St, Oklahoma City, OK 73104 USA Vet Affairs Med Ctr 151A,921 NE 13th St Oklahoma City OK USA 73104
Citazione:
T.R. Hartley et al., "Hypertension risk status and effect of caffeine on blood pressure", HYPERTENSIO, 36(1), 2000, pp. 137-141

Abstract

We compared the acute effects of caffeine on arterial blood pressure (BP) in 5 hypertension risk groups composed of a total of 182 men. We identified73 men with optimal BP, 28 with normal BP, 36 with high-normal BP, and 27 with stage 1 hypertension on the basis of resting BP; in addition, we included 18 men with diagnosed hypertension from a hypertension clinic. During caffeine testing, BP was measured after 20 minutes of rest and again at 45 to 60 minutes after the oral administration of caffeine (3.3 mg/kg or a fixed dose of 250 mg for an average dose of 260 mg). Caffeine raised both systolic and diastolic BP (SBP and DBP, respectively; P<0.0001 for both) in all groups. However, an ANCOVA revealed that the strongest response to caffeinewas observed among diagnosed men, followed by the stage 1 and high-normal groups and then by the normal and optimal groups (SBP F-4,F-175=5.06, P<0.0001; DBP F-4,F-175=3.02, P<0.02). Indeed, diagnosed hypertensive men had a pre-to-postdrug change in BP that was >1.5 times greater than the optimal group. The potential clinical relevance of caffeine-induced BP changes is seen in the BPs that reached the hypertensive range (SBP greater than or equal to 140 mm Hg or DBP greater than or equal to 90 mm Hg) after caffeine. During the predrug baseline, 78% of diagnosed hypertensive men and 4% of stage 1 men were hypertensive, whereas no others were hypertensive. After caffeine ingestion, 19% of the high-normal, 15% of the stage 1, and 89% of the diagnosed hypertensive groups fell into the hypertensive range. All subjectsfrom the optimal and normal groups remained normotensive. We conclude thathypertension risk status should take priority in future research regardingpresser effects of dietary intake of caffeine.

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Documento generato il 23/10/20 alle ore 11:33:07