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Titolo:
End-tidal carbon dioxide as a noninvasive indicator of cardiac index during circulatory shock
Autore:
Jin, XH; Weil, MH; Tang, WC; Povoas, H; Pernat, A; Xie, JL; Bisera, J;
Indirizzi:
Inst Crit Care Med, Palm Springs, CA USA Inst Crit Care Med Palm Springs CA USA it Care Med, Palm Springs, CA USA Univ So Calif, Sch Med, Los Angeles, CA USA Univ So Calif Los Angeles CA USA So Calif, Sch Med, Los Angeles, CA USA
Titolo Testata:
CRITICAL CARE MEDICINE
fascicolo: 7, volume: 28, anno: 2000,
pagine: 2415 - 2419
SICI:
0090-3493(200007)28:7<2415:ECDAAN>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOPULMONARY-RESUSCITATION; MYOCARDIAL DYSFUNCTION; PROGNOSTIC INDICATOR; BLOOD-FLOW; OUTPUT; MONITOR; ARREST; VENTILATION; TENSION; PCO2;
Keywords:
cardiac index; blood flow; end-tidal carbon dioxide tension; capnography; hemorrhagic shock; septic shock; cardiogenic shock; pig; Gram-negative bacteremia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Jin, XH Inst Crit Care Med, Palm Springs, CA USA Inst Crit Care Med Palm Springs CA USA Med, Palm Springs, CA USA
Citazione:
X.H. Jin et al., "End-tidal carbon dioxide as a noninvasive indicator of cardiac index during circulatory shock", CRIT CARE M, 28(7), 2000, pp. 2415-2419

Abstract

Objective: To document the relationships between cardiac index and end-tidal carbon dioxide tension (Petco(2)) during diverse low-flow states of circulatory shock. Design: Randomized, prospective, controlled studies on animal models of hemorrhagic, septic, and cardiogenic shock,Setting: University-affiliate research laboratory. Subjects: Sixteen anesthetized domestic pigs weighing 35-45 kg,Interventions: Hemorrhagic shock was induced in five pips by bleeding followed by reinfusion of shed blood. Septic shock was induced in five pigs by infusion of live Escherichia coil Cardiogenic shock followed an interval ofglobal myocardial ischemia after inducing and reversing ventricular fibrillation in six pigs,Measurements and Main Results: potco(2) was continuously measured. Cardiacindex was measured intermittently by using conventional thermodilution techniques. Cardiac index was correlated with Petco(2) by polynomial regression and Bland-Altman analyses. Petco(2) was highly correlated with cardiac index during hemorrhagic shock (r(2) = .69, p < .01), septic shock (r(2) = .65, p < .01), and cardiogenic shock (r(2) = .81, p < .01), Petco(2) predicted thermodilution cardiac index with bias of -11 +/- 27 (+/- 2 sD) ml/min/kgduring hemorrhagic shock, 1.3 +/- 20.4 (+/- 2 SD) ml/min/kg during septic shock, and -1 +/- 12 (+/- 2 sD) ml/min/kg during cardiogenic shock. Conclusions: Cardiac output and Petco(2) were highly related in diverse experimental models of circulatory shock in which cardiac output was reduced by >40% of baseline values. Therefore, measurement of Petco(2), is a noninvasive alternative far continuous assessment of cardiac output during low-flow circulatory shock states of diverse causes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:02:41