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Titolo:
Bronchial responsiveness to methacholine is increased in citrus red mite (Panonychus citri)-sensitive children without asthmatic symptoms
Autore:
Min, KU; Kim, YK; Park, HS; Lee, MH; Lee, BJ; Son, JW; Kim, YY; Cho, SH;
Indirizzi:
Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 110744, South Korea Seoul Natl Univ Seoul South Korea 110744 Med, Seoul 110744, South Korea Seoul Natl Univ, Med Res Ctr, Inst Allergy & Clin Immunol, Seoul, South Korea Seoul Natl Univ Seoul South Korea gy & Clin Immunol, Seoul, South Korea Ajou Univ, Sch Med, Dept Allergy & Clin Immunol, Suwon 441749, South KoreaAjou Univ Suwon South Korea 441749 in Immunol, Suwon 441749, South Korea Cheju Univ, Coll Med, Dept Paediat, Cheju, South Korea Cheju Univ Cheju South Korea Coll Med, Dept Paediat, Cheju, South Korea
Titolo Testata:
CLINICAL AND EXPERIMENTAL ALLERGY
fascicolo: 8, volume: 30, anno: 2000,
pagine: 1129 - 1134
SICI:
0954-7894(200008)30:8<1129:BRTMII>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALLERGIC RHINITIS; NEW-ZEALAND; HYPERRESPONSIVENESS; REACTIVITY; PREVALENCE; HISTAMINE;
Keywords:
citrus red mite; bronchial responsiveness; asthma; sensitization; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Cho, SH Seoul Natl Univ, Coll Med, Dept Internal Med, 28 Yungun Dong, Seoul 110744, South Korea Seoul Natl Univ 28 Yungun Dong Seoul South Korea 110744 uth Korea
Citazione:
K.U. Min et al., "Bronchial responsiveness to methacholine is increased in citrus red mite (Panonychus citri)-sensitive children without asthmatic symptoms", CLIN EXP AL, 30(8), 2000, pp. 1129-1134

Abstract

Background A recent investigation has suggested that citrus red mite (Panonychus citri, CRM) is a common sensitizing allergen among children living around citrus farms. Objective A cross-sectional survey was performed to evaluate the bronchialresponsiveness to methacholine in CRM-sensitive children without asthmaticsymptoms. Subjects and methods A total of 375 children living around citrus farms were enrolled in this study. There were 201 boys and 174 girls with a mean age of 12.5 (range 7-16) years. Each subject was evaluated by a questionnaire, a skin prick test with 13 common inhalant allergens including CRM, and a methacholine bronchial provocation test (MBPT). Results Positive rate of MBPT (PC20-methacholine < 25 mg/mL) was higher inatopic rhinitic and atopic control children than in nonatopic rhinitic andnonatopic control subjects (41.3% and 33.3% vs 17.2% and 15.4%, respectively, both P < 0.05). Slope of dose-response curve (DRS, %/mg/mL) was higher in atopic rhinitic children than in nonatopic rhinitic, atopic control and nonatopic control subjects (14.3 +/- 0.87 vs 9.4 +/- 0.72, 10.0 +/- 1.37 and 9.2 +/- 1.51, P < 0.05, respectively). Both the positive rate of MBPT andthe DRS were increased in children with positive skin response to CRM thanin those without sensitization (48.2% vs 22.9%, P = 0.0001; 15.6 +/- 1.26 vs 10.2 +/- 0.65, P = 0.0001). Conclusion Bronchial responsiveness is increased in citrus red mite-sensitive children even if they have no asthmatic symptoms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/02/20 alle ore 20:22:55