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Titolo:
Comparison of immunogenicity and reactogenicity of a measles, mumps and rubella (MMR) vaccine in German children vaccinated at 9-11, 12-14 or 15-17 months of age
Autore:
Klinge, J; Lugauer, S; Korn, K; Heininger, U; Stehr, K;
Indirizzi:
Univ Erlangen Nurnberg, Hosp Children & Adolescents, D-8520 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-8520 D-8520 Erlangen, Germany Univ Erlangen Nurnberg, Inst Clin & Mol Virol, D-8520 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-8520 D-8520 Erlangen, Germany
Titolo Testata:
VACCINE
fascicolo: 27, volume: 18, anno: 2000,
pagine: 3134 - 3140
SICI:
0264-410X(20000715)18:27<3134:COIARO>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNE-RESPONSE; INFANTS BORN; ANTIBODY-TITERS; MOTHERS; POPULATION; IMMUNIZATION; 6-MONTH-OLD; WOMEN; ERA;
Keywords:
measles; mumps; rubella-immunisation; immunisation age; seroconversion rate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Heininger, U Univ Basel, Childrens Hosp, POB, CH-4005 Basel, Switzerland Univ Basel POB Basel Switzerland CH-4005 Basel, Switzerland
Citazione:
J. Klinge et al., "Comparison of immunogenicity and reactogenicity of a measles, mumps and rubella (MMR) vaccine in German children vaccinated at 9-11, 12-14 or 15-17 months of age", VACCINE, 18(27), 2000, pp. 3134-3140

Abstract

Children aged 9-11, 12-14 or 15-17 months, respectively were vaccinated with a measles, mumps and rubella (MMR) vaccine and serum antibody responses and reactogenicity were compared. The data of 118 children could he analysed (group 1=9-11 months, n = 46; group 2=12-14 months, n = 29, group 3, 15-17 months, n = 43). The only significant difference observed was for seroconversion against measles virus between group 1 and group 3 (84.8% vs 100%, p= 0.012). No serious adverse events were reported. Local side reactions were mild, infrequent and independent of age. Immunisation against MMR is safe and effective even when administered before the currently recommended ageof 12 months. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 09:31:45