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Titolo:
'Is MDMA a human neurotoxin?': Diverse views from the discussants
Autore:
Turner, JJD; Parrott, AC;
Indirizzi:
Univ E London, Dept Psychol, London E15 4LZ, England Univ E London London England E15 4LZ pt Psychol, London E15 4LZ, England
Titolo Testata:
NEUROPSYCHOBIOLOGY
fascicolo: 1, volume: 42, anno: 2000,
pagine: 42 -
SICI:
0302-282X(2000)42:1<42:'MAHND>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ECSTASY MDMA; RECREATIONAL USE;
Keywords:
MDMA; neurotoxin;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Turner, JJD Univ E London, Dept Psychol, London E15 4LZ, England Univ E London London England E15 4LZ London E15 4LZ, England
Citazione:
J.J.D. Turner e A.C. Parrott, "'Is MDMA a human neurotoxin?': Diverse views from the discussants", NEUROPSYCHB, 42(1), 2000, pp. 42

Abstract

Every discussant at the Novartis symposium was invited to submit a 250-word abstract, giving their views upon the question: 'Is MDMA a human neurotoxin?'. These abstracts are presented here. They illustrate a wide range of viewpoints and opinions, as might be expected from experts in such diverse fields: animal neuroscience, human cognitive testing, police pathology laboratory, psychotherapeutic institute and psychiatric hospital. Some abstractsemphasized the methodological weaknesses of the human empirical data: the uncertain nature of 'Ecstasy' tablets, the reliance on self-report data, and the contributory factors of heat, dancing/exertion, poor diet and other illicit drugs. These factors may lead to psychobiological changes, which could be misinterpreted as neural damage. The absence of gliosis in animal models was also noted, which led to suggestions that there might be alternative interpretations for the neural changes which have been observed in rats and monkeys. Others noted the absence of neural/behavioural change followinga single Ecstasy tablet, or commented upon the therapeutic benefits of MDMA in a quiet supportive environment. Nevertheless, novel studies from England, Germany, Italy, the Netherlands, Scotland and Wales confirmed and extended the range of cognitive, behavioural, EEG and neurological deficits, displayed by drug-free Ecstasy users. Moreover, these deficits often remained when other illicit drug use was statistically controlled. In conclusion: IfMDMA neurotoxicity in humans is a myth, then it is a myth with a heavy serotonergic component. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:43:26