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Titolo:
Gastric anti-secretory and anti-ulcerogenic effects of Dombeya buettneri in rats
Autore:
Okwari, OO; Ettarh, RR; Akpogomeh, BA; Eteng, MU;
Indirizzi:
Univ Calabar, Coll Med Sci, Dept Physiol, Calabar, Nigeria Univ Calabar Calabar Nigeria ll Med Sci, Dept Physiol, Calabar, Nigeria Univ Calabar, Coll Med Sci, Dept Biochem, Calabar, Nigeria Univ Calabar Calabar Nigeria ll Med Sci, Dept Biochem, Calabar, Nigeria
Titolo Testata:
JOURNAL OF ETHNOPHARMACOLOGY
fascicolo: 1-2, volume: 71, anno: 2000,
pagine: 315 - 319
SICI:
0378-8741(200007)71:1-2<315:GAAAEO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUCOSAL;
Keywords:
Dombeya buettneri; gastric acid secretion; histamine; ethanol-induced ulcer; mucus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Ettarh, RR Univ Calabar, Coll Med Sci, Dept Physiol, PMB 1115, Calabar, Nigeria Univ Calabar PMB 1115 Calabar Nigeria 1115, Calabar, Nigeria
Citazione:
O.O. Okwari et al., "Gastric anti-secretory and anti-ulcerogenic effects of Dombeya buettneri in rats", J ETHNOPHAR, 71(1-2), 2000, pp. 315-319

Abstract

The effects of an aqueous extract of the leaves of Dombeya buettneri on gastric acid secretion and ethanol-induced gastric mucosal damage were studied in rats. Gastric acid secretion was measured by continuous perfusion in urethane-anaesthetised rats. Intragastric perfusion with the extract caused significant reduction in basal and histamine-stimulated gastric acid secretion. Pretreatment with the extract also reduced the extent of gastric mucosal damage induced by oral ethanol (75% v/v), but had no effect on mucus secretion. It is suggested that the consumption of an extract of the leaves ofD. buettneri may be beneficial in the prevention and treatment of peptic ulcer disease. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/06/20 alle ore 14:22:56