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Titolo:
Notch signal transduction: a real Rip and more
Autore:
Weinmaster, G;
Indirizzi:
Univ Calif Los Angeles, UCLA Sch Med, Dept Biol Chem, Ctr Hlth Sci 33 257,Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
CURRENT OPINION IN GENETICS & DEVELOPMENT
fascicolo: 4, volume: 10, anno: 2000,
pagine: 363 - 369
SICI:
0959-437X(200008)10:4<363:NSTARR>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMYLOID PRECURSOR PROTEIN; ALPHA-SECRETASE CLEAVAGE; CAENORHABDITIS-ELEGANS; ALZHEIMERS-DISEASE; GAMMA-SECRETASE; DROSOPHILA DEVELOPMENT; INTRACELLULAR DOMAIN; PROTEOLYTIC RELEASE; NUCLEAR ACCESS; PRESENILIN-1;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
65
Recensione:
Indirizzi per estratti:
Indirizzo: Weinmaster, G Univ Calif Los Angeles, UCLA Sch Med, Dept Biol Chem, Ctr Hlth Sci 33 257,Box 951737, Los Angeles, CA 90095 USA Univ Calif Los Angeles Box 951737 Los Angeles CA USA 90095 A
Citazione:
G. Weinmaster, "Notch signal transduction: a real Rip and more", CUR OP GEN, 10(4), 2000, pp. 363-369

Abstract

The Notch signaling pathway functions in a wide variety of processes that regulate tissue patterning and morphogenesis in developing vertebrates and invertebrates. Research on the mechanism of ligand-induced Notch signal transduction has revealed a novel and essential element in the signal cascade. Some recent findings support a model in which sequential proteolytic cleavage serves to regulate Notch signal transduction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 03:00:12