Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Living without oxygen: lessons from the freshwater turtle
Autore:
Jackson, DC;
Indirizzi:
Brown Univ, Dept Mol Pharmacol Physiol & Biotechnol, Providence, RI 02912 USA Brown Univ Providence RI USA 02912 & Biotechnol, Providence, RI 02912 USA
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
fascicolo: 3, volume: 125, anno: 2000,
pagine: 299 - 315
SICI:
1095-6433(200003)125:3<299:LWOLFT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRYSEMYS-PICTA-BELLII; ANOXIA-TOLERANT HEPATOCYTES; SEVERELY HYPOXIC WATER; LONG-TERM SUBMERGENCE; ACID-BASE STATUS; PROLONGED SUBMERGENCE; ANAEROBIC METABOLISM; PROTEIN-SYNTHESIS; PAINTED TURTLES; LACTIC-ACIDOSIS;
Keywords:
acid-base balance; anaerobiosis; anoxia; buffering; bone; lactic acid; metabolic depression; metabolic rate; strong ion difference; turtle shell;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
82
Recensione:
Indirizzi per estratti:
Indirizzo: Jackson, DC Brown Univ, Dept Mol Pharmacol Physiol & Biotechnol, Box G, Providence, RI02912 USA Brown Univ Box G Providence RI USA 02912 ovidence, RI02912 USA
Citazione:
D.C. Jackson, "Living without oxygen: lessons from the freshwater turtle", COMP BIOC A, 125(3), 2000, pp. 299-315

Abstract

Freshwater turtles, and specifically, painted turtles, Chrysemys picta, are the most anoxia-tolerant air-breathing vertebrates. These animals can survive experimental anoxic submergences lasting up to 5 months at 3 degrees C. Two general integrative adaptations underlie this remarkable capacity. First is a profound reduction in energy metabolism to approximate to 10% of the normoxic rate at the same temperature. This is a coordinated reduction of both ATP generating mechanisms and ATP consuming pathways of the cells. Second is a defense of acid-base state in response to the extreme lactic acidosis that results from anaerobic glycolysis. Central to this defense is anexploitation of buffer reserves within the skeleton and, in particular, the turtle's shell, its most characteristic structure. Carbonates are released from bone and shell to enhance body fluid buffering of lactic acid and lactic acid moves into shell and bone where it is buffered and stored. The combination of slow metabolic rate and a large and responsive mineral reserveare key to this animal's extraordinary anaerobic capacity. (C) 2000 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:29:44