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Titolo:
Case studies of the hepatitis B patient: A panel discussion
Autore:
Vierling, JM; Teperman, LW; Lake, JR; Perrillo, RP; Peters, M; Fried, M; Schiff, ER;
Indirizzi:
Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA Cedars Sinai Med Ctr Los Angeles CA USA 90048 , Los Angeles, CA 90048 USA NYU, New York, NY USA NYU New York NY USANYU, New York, NY USA Univ Minnesota, Minneapolis, MN USA Univ Minnesota Minneapolis MN USAUniv Minnesota, Minneapolis, MN USA Alton Ochsner Med Fdn & Ochsner Clin, New Orleans, LA 70121 USA Alton Ochsner Med Fdn & Ochsner Clin New Orleans LA USA 70121 A 70121 USA Univ Calif San Francisco, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Emory Univ, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322Emory Univ, Atlanta, GA 30322 USA Univ Miami, Miami, FL 33152 USA Univ Miami Miami FL USA 33152Univ Miami, Miami, FL 33152 USA
Titolo Testata:
SEMINARS IN LIVER DISEASE
, volume: 20, anno: 2000, supplemento:, 1
pagine: 29 - 35
SICI:
0272-8087(2000)20:<29:CSOTHB>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ORTHOTOPIC LIVER-TRANSPLANTATION; HEPATOCELLULAR-CARCINOMA; ADEFOVIR DIPIVOXIL; PASSIVE-IMMUNIZATION; IMMUNE GLOBULIN; VIRUS; PROPHYLAXIS; CIRRHOSIS; THERAPY; TRIAL;
Keywords:
liver transplantation; hepatitis B; case studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Schiff, ER Ctr Liver Dis, 1500 NW 12th Ave,Suite 1101, Miami, FL 33136 USACtr Liver Dis 1500 NW 12th Ave,Suite 1101 Miami FL USA 33136 SA
Citazione:
J.M. Vierling et al., "Case studies of the hepatitis B patient: A panel discussion", SEM LIV DIS, 20, 2000, pp. 29-35

Abstract

In recent years, there have been significant advances in the treatment of patients with hepatitis B who are candidates for liver transplantation. This includes the prevention and management of hepatitis B posttransplantation. However; there is no established protocol for treating these patients. Ultimately: the goal would be to have patients HBV-DNA negative pretransplantation and then to prevent HBV recurrence posttransplantation to help ensuretheir quality of life. Several clinical case scenarios are presented and possible treatment solutions have beer? suggested The riming of a transplantis critical due to the risk of viral mutation while the patient is on a nucleoside analogue antiviral agent and waiting for an organ. One successful option might be to start therapy pretransplant and continue it posttransplant. Combination therapy appears to provide the most effective course of treatment. This should include a nucleoside analogue and patients should he covered with hepatitis B immune globulin throughout the course of therapy. Several other variations of combination therapy are discussed but many clinical issues remain to be resolved. Guidelines for future studies designed to answer these questions are proposed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 14:12:11