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Titolo:
The value of repeated echocardiographic evaluation in patients with idiopathic dilated cardiomyopathy during treatment with metoprolol or captopril
Autore:
Jansson, K; Dahlstrom, U; Karlberg, KE; Karlsson, E; Nyquist, O; Nylander, E;
Indirizzi:
Linkoping Univ Hosp, Linkoping Heart Ctr, Dept Cardiol, SE-58185 Linkoping, Sweden Linkoping Univ Hosp Linkoping Sweden SE-58185 SE-58185 Linkoping, Sweden Huddinge Univ Hosp, Dept Cardiol, S-14186 Huddinge, Sweden Huddinge Univ Hosp Huddinge Sweden S-14186 iol, S-14186 Huddinge, Sweden
Titolo Testata:
SCANDINAVIAN CARDIOVASCULAR JOURNAL
fascicolo: 3, volume: 34, anno: 2000,
pagine: 293 - 300
SICI:
1401-7431(200006)34:3<293:TVOREE>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC HEART-FAILURE; VENTRICULAR DIASTOLIC FUNCTION; DOPPLER; MORTALITY; DYSFUNCTION; ULTRASOUND; MORBIDITY; ENALAPRIL; DISEASE;
Keywords:
captopril; dilated cardiomyopathy; echocardiography; left ventricle; metoprolol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Jansson, K Linkoping Univ Hosp, Linkoping Heart Ctr, Dept Cardiol, SE-58185 Linkoping, Sweden Linkoping Univ Hosp Linkoping Sweden SE-58185 nkoping, Sweden
Citazione:
K. Jansson et al., "The value of repeated echocardiographic evaluation in patients with idiopathic dilated cardiomyopathy during treatment with metoprolol or captopril", SC CARDIOVA, 34(3), 2000, pp. 293-300

Abstract

Serial echocardiographic investigations were carried out on patients with idiopathic dilated cardiomyopathy, to evaluate treatment effects on left ventricular (LV) performance during therapy with either metoprolol or captopril. Thirty-two patients (23 males and 9 females) with mild to moderate symptoms of heart failure (NYHA II-III) and a mean age of 49 years were included in the investigation. The patients were investigated with Doppler echocardiography before treatment, after 3 and 6 months of treatment (either metoprolol or captopril) and 1 month after withdrawal of treatment. Intra- and inter-investigator reproducibility was acceptable, with a coefficient of variation of less than 5% for LV dimensions. A reduction in LV dimensions was seen in both treatment groups. In the metoprolol group there was also an increase in LV stroke volume and fractional shortening. The non-invasive datawere in accordance with invasive measurements of stroke volume and LV filling pressure. In patients with idiopathic dilated cardiomyopathy and mild to moderate symptoms of heart failure, echocardiography seemed to be sufficiently reproducible to be used for determination of treatment effects in a longitudinal heart failure study. Both metoprolol and captopril were well tolerated and had favourable effects on LV performance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 13:01:07