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Titolo:
Magnesium transport from aqueous solutions across Caco-2 cells - an experimental model for intestinal bioavailability studies. Physiological considerations and recommendations
Autore:
Ekmekcioglu, C; Ekmekcioglu, A; Marktl, W;
Indirizzi:
Univ Vienna, Dept Med Physiol, A-1090 Vienna, Austria Univ Vienna ViennaAustria A-1090 pt Med Physiol, A-1090 Vienna, Austria
Titolo Testata:
MAGNESIUM RESEARCH
fascicolo: 2, volume: 13, anno: 2000,
pagine: 93 - 102
SICI:
0953-1424(200006)13:2<93:MTFASA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VITRO; IRON AVAILABILITY; DIETARY CALCIUM; INVITRO METHOD; LINE CACO-2; NUDE-MICE; ABSORPTION; SYSTEM; RATS; INVIVO;
Keywords:
Caco-2 cells; magnesium transport; aqueous solutions;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Ekmekcioglu, C Univ Vienna, Dept Med Physiol, Schwarzpanierstr 17, A-1090 Vienna, Austria Univ Vienna Schwarzpanierstr 17 Vienna Austria A-1090 tria
Citazione:
C. Ekmekcioglu et al., "Magnesium transport from aqueous solutions across Caco-2 cells - an experimental model for intestinal bioavailability studies. Physiological considerations and recommendations", MAGNES RES, 13(2), 2000, pp. 93-102

Abstract

The Caco-2 cell model is gaining more and more importance as an in vitro method to study intestinal nutrient bioavailability from foods. In a previous article we presented evidence that fractional Mg2+ transport from different aqueous solutions containing differing amounts of magnesium varies considerably in some cases. In the present article we discuss the role of electrolytes, such as calcium and the anions HCO3-, SO42- and Cl-, in modulating magnesium absorption. Another purpose of this manuscript is to give recommendations, based mainly on physiological knowledge, which can be helpful when planning and conducting intestinal bioavailability studies using either the Caco-2 culture system or other in vitro models in order to achieve nearly similar conditions as in vivo.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 16:09:54