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Titolo:
Chemically assisted dissection of tissues: An interesting support in abdominal myomectomy
Autore:
Benassi, L; Lopopolo, G; Pazzoni, F; Ricci, L; Kaihura, C; Piazza, F; Vadora, E; Zini, C;
Indirizzi:
Univ Parma, Dept Obstet & Gynecol, I-43100 Parma, Italy Univ Parma ParmaItaly I-43100 pt Obstet & Gynecol, I-43100 Parma, Italy Univ Parma, Ear Nose Throat Dept, I-43100 Parma, Italy Univ Parma Parma Italy I-43100 ar Nose Throat Dept, I-43100 Parma, Italy
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
fascicolo: 1, volume: 191, anno: 2000,
pagine: 65 - 69
SICI:
1072-7515(200007)191:1<65:CADOTA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
2-MERCAPTOETHANE SULFONATE MESNA; PREVENTION; SURGERY; HYSTERECTOMY; LAPAROSCOPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Benassi, L Univ Parma, Dept Obstet & Gynecol, Via Gramsci 14, I-43100 Parma, Italy Univ Parma Via Gramsci 14 Parma Italy I-43100 100 Parma, Italy
Citazione:
L. Benassi et al., "Chemically assisted dissection of tissues: An interesting support in abdominal myomectomy", J AM COLL S, 191(1), 2000, pp. 65-69

Abstract

Background: The aim of this study was to verify the efficacy of sodium-2-mercaptoethanesulfonate (mesna) in the chemical separation of tissues in abdominal myomectomies when used with the traditional mechanical separation techniques. Study Design: In a prospective, randomized study, 58 women under-went abdominal myomectomy. In 29 of these, we used mesna for highlighting and separating tissues, and in the other 29 we used saline solution for the same purposes. The variables evaluated included the number of myomas removed, the volume of the biggest myoma, and the total volume of the myomas removed in every intervention. We also recorded operating time, the length of hospital stay, the degree of procedure difficulty perioperative blood loss, operativecomplications, and cost. Results: The operation was significantly shorter in the mesna group (p < 0.05) even though the volume and the number of myomas were larger. The degree of difficulty evaluated by the surgeon at the end of every operation was not significantly different in the two groups. The reduction in hemoglobin 24 hours after operation was significantly less in the patients treated with mesna (p = 0.006), but this difference was probably altered by the increase in hematocrit levels. Conclusions: Because of its ability as a chemical dissector, mesna may be a useful aid in this type of benign gynecologic operation. Larger studies to confirm this are needed. (J Am Cell Surg 2000;191:65-69. (C) 2000 by the American College of Surgeons).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 22:29:37